{"id":1289,"date":"2026-07-21T16:03:07","date_gmt":"2026-07-21T13:03:07","guid":{"rendered":"https:\/\/life-peptide.com\/?post_type=product&#038;p=1289"},"modified":"2026-07-21T16:03:09","modified_gmt":"2026-07-21T13:03:09","slug":"nad","status":"publish","type":"product","link":"https:\/\/life-peptide.com\/cs\/product\/nad\/","title":{"rendered":"NAD+ \/ 500 mg"},"content":{"rendered":"<p>NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme found in every living cell.\u00a0Rather than acting as a signalling peptide or hormone, NAD+ functions as an essential electron carrier in hundreds of metabolic reactions, playing a central role in <strong>ATP production, mitochondrial function and cellular repair<\/strong>.<\/p>\n<p>Because NAD+ levels naturally decline with age and metabolic stress, it has become one of the most extensively investigated molecules in research on <strong>aging, energy metabolism and mitochondrial biology<\/strong>.<\/p>\n<hr \/>\n<h4><strong>Why NAD+ is widely investigated<\/strong><\/h4>\n<p>Published research has investigated NAD+ in relation to:<\/p>\n<ul>\n<li>cellular energy production<\/li>\n<li>mitochondrial function<\/li>\n<li>healthy aging<\/li>\n<li>DNA repair<\/li>\n<li>oxidative stress<\/li>\n<li>metabolic health<\/li>\n<li>cognitive function<\/li>\n<li>muscle physiology<\/li>\n<li>sirtuin biology<\/li>\n<\/ul>\n<p>Unlike mitochondrial peptides, NAD+ serves as a fundamental metabolic cofactor required for normal cellular function across virtually every tissue.<\/p>\n<h4><strong>How NAD+ works<\/strong><\/h4>\n<p><strong>Cellular energy production<\/strong><\/p>\n<p>NAD+ plays a central role in converting nutrients into usable cellular energy.\u00a0It transfers electrons during glycolysis, the citric acid cycle and oxidative phosphorylation, allowing mitochondria to generate ATP efficiently.<\/p>\n<p><strong>Mitochondrial function<\/strong><\/p>\n<p>Healthy mitochondria depend on adequate NAD+ availability to support normal energy metabolism.\u00a0Research has investigated how declining NAD+ levels influence mitochondrial performance during aging and metabolic stress.<\/p>\n<p><strong>DNA repair<\/strong><\/p>\n<p>NAD+ serves as an essential substrate for enzymes involved in DNA repair, including PARPs, which respond to DNA damage by helping maintain genomic stability.<\/p>\n<p><strong>Sirtuin activation<\/strong><\/p>\n<p>NAD+ is also required by sirtuins, a family of enzymes involved in cellular stress responses, metabolism and healthy aging.\u00a0This relationship has made NAD+ a central focus of longevity research.<\/p>\n<hr \/>\n<h4><strong>Why NAD+ is different from mitochondrial peptides<\/strong><\/h4>\n<p>Although frequently discussed together, NAD+, SS-31 and MOTS-c investigate different aspects of mitochondrial biology.<\/p>\n<p><strong>NAD+<\/strong> supplies an essential coenzyme required for cellular energy metabolism.<br \/>\n<a href=\"https:\/\/life-peptide.com\/cs\/product\/ss-31\/\"><strong>SS-31<\/strong><\/a> investigates mitochondrial membrane integrity and ATP production.<br \/>\n<a href=\"https:\/\/life-peptide.com\/cs\/product\/mots-c-10-mg\/\"><strong>MOTS-c<\/strong> <\/a>studies metabolic signalling and adaptive cellular responses.<\/p>\n<p>Together, these represent complementary areas of cellular energy research rather than competing mechanisms.<\/p>\n<h4><strong>Lidsk\u00fd a preklinick\u00fd v\u00fdzkum<\/strong><\/h4>\n<p>NAD+ has been investigated extensively in both laboratory and clinical settings.<\/p>\n<p>Current research explores its role in <strong>aging, metabolic disorders, neurodegeneration, cardiovascular physiology and mitochondrial disease<\/strong>. Much of this work also focuses on strategies to increase intracellular NAD+ through precursors such as NMN and nicotinamide riboside, reflecting the importance of NAD+ homeostasis in human physiology.<\/p>\n<p>Although the biological importance of NAD+ is well established, many therapeutic applications remain under active investigation.<\/p>\n<h4><strong>Publikovan\u00e9 bezpe\u010dnostn\u00ed poznatky<\/strong><\/h4>\n<p>As a naturally occurring cellular coenzyme, NAD+ has been the subject of extensive biological research.<\/p>\n<p>Clinical investigations have generally reported favourable tolerability across a range of study designs, although research continues to evaluate optimal delivery methods, pharmacokinetics and potential applications in age-related disease.<\/p>\n<hr \/>\n<h3><strong>Vlastnosti produktu<\/strong><\/h3>\n<p>Aplikace: laboratorn\u00ed a analytick\u00fd v\u00fdzkum<br \/>\nPou\u017eit\u00ed omezen\u00e9: nen\u00ed ur\u010deno k lidsk\u00e9 spot\u0159eb\u011b; pro l\u00e9ka\u0159sk\u00e9, veterin\u00e1rn\u00ed ani kosmetick\u00e9 pou\u017eit\u00ed<br \/>\nVyrobeno v za\u0159\u00edzen\u00edch spl\u0148uj\u00edc\u00edch spr\u00e1vnou v\u00fdrobn\u00ed praxi (GMP) za p\u0159\u00edsn\u00fdch protokol\u016f kontroly kvality.<br \/>\nKa\u017ed\u00e1 \u0161ar\u017ee je po v\u00fdrob\u011b pe\u010dliv\u011b laboratorn\u011b testov\u00e1na (Certifik\u00e1t o anal\u00fdze najdete pod obr\u00e1zky produkt\u016f).<br \/>\nLyofilizov\u00e1no (su\u0161eno mrazem) pro maxim\u00e1ln\u00ed stabilitu a prodlou\u017eenou trvanlivost.<br \/>\nUzav\u0159eno ve steriln\u00edch lahvi\u010dk\u00e1ch, p\u0159ipraveno k rekonstituci.<br \/>\nPurity: \u2265 99.47% , HPLC tested<br \/>\nVzhled: b\u00edl\u00fd lyofilizovan\u00fd pr\u00e1\u0161ek<br \/>\nMolecular formula:\u00a0C<sub>21<\/sub>H<sub>29<\/sub>N<sub>7<\/sub>O<sub>14<\/sub>P<sub>2<\/sub><sup>2+<\/sup><br \/>\nMolecular weight: 665.4<\/p>\n<p><strong>\u00dalo\u017ei\u0161t\u011b<\/strong>Neotev\u0159en\u00e9 lyofilizovan\u00e9 lahvi\u010dky jsou nejl\u00e9pe skladov\u00e1ny <strong>chlazen\u00e9 p\u0159i 2\u20138 \u00b0C<\/strong>, co\u017e je metoda skladov\u00e1n\u00ed potvrzen\u00e1 na\u0161\u00edm v\u00fdrobn\u00edm partnerem a vhodn\u00e1 a\u017e po dobu 24 m\u011bs\u00edc\u016f. Preferuje se chlazen\u00ed, proto\u017ee minimalizuje zbyte\u010dn\u00e9 cykly zmrazov\u00e1n\u00ed a rozmrazov\u00e1n\u00ed b\u011bhem b\u011b\u017en\u00e9 manipulace. Pokud je vy\u017eadov\u00e1no podstatn\u011b del\u0161\u00ed skladov\u00e1n\u00ed, lze zmrazen\u00e9 uchov\u00e1vat i neotev\u0159en\u00e9 lyofilizovan\u00e9 lahvi\u010dky. Po rekonstituci v\u017edy skladujte p\u0159i 2\u20138 \u00b0C a nezmrazujte.<\/p>\n<h4><strong>Rekonstituce a manipulace<\/strong><\/h4>\n<p>NAD+ is supplied as a lyophilised vial and should be handled using standard peptide reconstitution procedures appropriate to the research setting. Must be reconstituted with <a href=\"https:\/\/life-peptide.com\/cs\/product\/bac-10-ml\/\">bakteriostatick\u00e1 voda<\/a> p\u0159ed pou\u017eit\u00edm. Pro zachov\u00e1n\u00ed struktur\u00e1ln\u00ed integrity p\u0159idejte zvolen\u00e9 rozpou\u0161t\u011bdlo pomalu po vnit\u0159n\u00ed st\u011bn\u011b lahvi\u010dky nam\u00edsto p\u0159\u00edmo na peptidov\u00fd pr\u00e1\u0161ek a vyhn\u011bte se prudk\u00e9mu prot\u0159ep\u00e1v\u00e1n\u00ed. Jemn\u00e9 krou\u017een\u00ed je obecn\u011b dosta\u010duj\u00edc\u00ed, jakmile se peptid zcela rozpust\u00ed. Standardn\u00ed laboratorn\u00ed postupy zahrnuj\u00ed tak\u00e9 ponech\u00e1n\u00ed chlazen\u00fdch lahvi\u010dek dos\u00e1hnout pokojov\u00e9 teploty p\u0159ed rekonstituc\u00ed, aby se minimalizovala kondenzace uvnit\u0159 lahvi\u010dky.<\/p>\n<p>Pro dal\u0161\u00ed pokyny k v\u00fdb\u011bru rozpou\u0161t\u011bdla, pl\u00e1nov\u00e1n\u00ed koncentrac\u00ed a skladov\u00e1n\u00ed viz \u00fapln\u00e9 <a href=\"https:\/\/life-peptide.com\/cs\/reconstitution-of-peptides\/\">Pr\u016fvodce rekonstituc\u00ed peptid\u016f<\/a> a <a href=\"https:\/\/life-peptide.com\/cs\/calculator\/\">Kalkula\u010dka rekonstituce<\/a>.<\/p>\n<hr \/>\n<h4><strong>Vybran\u00e9 v\u00fdzkumn\u00e9 reference<\/strong><\/h4>\n<ul>\n<li>Covarrubias AJ, Perrone R, Grozio A, Verdin E. <em>NAD+ Metabolism and Its Roles in Cellular Processes During Ageing, Nature Reviews Molecular Cell Biology<\/em>, 2021.<\/li>\n<\/ul>\n<p>A comprehensive review of NAD+ biology, aging, metabolism and mitochondrial function.<\/p>\n<ul>\n<li>Yoshino J, Baur JA, Imai SI. <em>NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and Nicotinamide Riboside, Cell Metabolism<\/em>, 2018.<\/li>\n<\/ul>\n<p>A landmark review summarising NAD+ metabolism and strategies for restoring intracellular NAD+.<\/p>\n<ul>\n<li>Rajman L, Chwalek K, Sinclair DA.<em> Therapeutic Potential of NAD+ Boosting Molecules, Nature Reviews Drug Discovery<\/em>, 2018.<\/li>\n<\/ul>\n<p>A detailed overview of NAD+ biology and current therapeutic research.<\/p>\n<hr \/>\n<h4><strong>\u010casto kladen\u00e9 ot\u00e1zky<\/strong><\/h4>\n<p><strong>What is NAD+?<\/strong><\/p>\n<p>NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme essential for cellular energy production, mitochondrial function and DNA repair.<\/p>\n<p><strong>Is NAD+ a peptide?<\/strong><\/p>\n<p>No. NAD+ is not a peptide. It is a naturally occurring coenzyme found in every living cell and plays a central role in energy metabolism.<\/p>\n<p><strong>Why is NAD+ important for mitochondria?<\/strong><\/p>\n<p>NAD+ acts as an electron carrier during cellular respiration, allowing mitochondria to produce ATP efficiently and maintain normal energy metabolism.<\/p>\n<p><strong>How is NAD+ different from MOTS-c?<\/strong><\/p>\n<p>Although both investigate mitochondrial biology, NAD+ functions as an essential metabolic coenzyme, whereas MOTS-c acts as a mitochondrial signalling peptide that regulates cellular metabolism.<\/p>\n<p><strong>How is NAD+ different from SS-31?<\/strong><\/p>\n<p>SS-31 investigates the structural integrity of mitochondria by targeting the inner mitochondrial membrane, while NAD+ serves as a fundamental coenzyme required for cellular energy production.<\/p>\n<p><strong>Je tento produkt ur\u010den k lidsk\u00e9mu pou\u017eit\u00ed?<\/strong><\/p>\n<p>No. NAD+ supplied by LIFE Peptide is intended strictly for laboratory and analytical research. It is not intended for human consumption, diagnosis, treatment or prevention of disease.<\/p>\n<hr \/>\n<h4><strong>Souvisej\u00edc\u00ed v\u00fdzkumn\u00fd kontext<\/strong><\/h4>\n<p>NAD+ is frequently discussed alongside other research compounds investigating cellular energy, mitochondrial biology and healthy aging, although each targets distinct biological mechanisms.<\/p>\n<p><a href=\"https:\/\/life-peptide.com\/cs\/product\/ss-31\/\">SS-31<\/a> (Elamipretide) \u2013 investigated for mitochondrial repair and cellular energy production.<br \/>\n<a href=\"https:\/\/life-peptide.com\/cs\/product\/mots-c-10-mg\/\">MOTS-c<\/a> \u2013 studied for metabolic signalling and exercise adaptation.<br \/>\n<a href=\"https:\/\/life-peptide.com\/cs\/product\/epitalon-10-mg\/\">Epitalon<\/a> \u2013 investigated for telomere biology and healthy aging research.<br \/>\n<a href=\"https:\/\/life-peptide.com\/cs\/product\/ghk-cu-50-mg\/\">GHK-Cu<\/a> \u2013 studied for tissue regeneration and cellular repair.<br \/>\n<a href=\"https:\/\/life-peptide.com\/cs\/product\/cjc-1295-with-dac\/\">CJC-1295 s DAC<\/a> \u2013 investigated for sustained GH and IGF-1 signalling.<\/p>\n<p><strong>POZN\u00c1MKA<\/strong>Toto je pouze pro vzd\u011bl\u00e1vac\u00ed \u00fa\u010dely a nep\u0159edstavuje l\u00e9ka\u0159skou radu.<\/p>\n<p><strong>Z\u0159eknut\u00ed se odpov\u011bdnosti<\/strong><br \/>\nTento produkt je prod\u00e1v\u00e1n pouze pro v\u00fdzkumn\u00e9 \u00fa\u010dely. Nen\u00ed ur\u010den k diagnostice, l\u00e9\u010db\u011b, vyl\u00e9\u010den\u00ed nebo prevenci jak\u00fdchkoli onemocn\u011bn\u00ed. Kupuj\u00edc\u00ed p\u0159eb\u00edr\u00e1 plnou odpov\u011bdnost za \u0159\u00e1dnou manipulaci a pou\u017eit\u00ed.<\/p>","protected":false},"excerpt":{"rendered":"<p>NAD+ (Nicotinamide Adenine Dinucleotide) 500 mg is a research-grade cellular coenzyme supplied in lyophilised form for laboratory use. As one of the most essential molecules in cellular metabolism, NAD+ is widely investigated for mitochondrial function, energy production, DNA repair and healthy aging research.<\/p>\n<p>||<\/p>\n<p>Purity \u226599% | EU Shipping from \u20ac5 | Free shipping upgrades available | Card payments accepted<\/p>","protected":false},"featured_media":1287,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[131],"product_tag":[361,329,383,325,384,382,364,380,381],"class_list":["post-1289","product","type-product","status-publish","has-post-thumbnail","product_cat-cellular-mitochondrial-research","product_tag-atp-production","product_tag-cellular-energy","product_tag-dna-repair","product_tag-healthy-aging","product_tag-longevity-research","product_tag-mitochondrial-function","product_tag-mitochondrial-research","product_tag-nad","product_tag-nicotinamide-adenine-dinucleotide","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/product\/1289","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/comments?post=1289"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/media\/1287"}],"wp:attachment":[{"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/media?parent=1289"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/product_brand?post=1289"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/product_cat?post=1289"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/product_tag?post=1289"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}