{"id":910,"date":"2026-04-27T16:55:29","date_gmt":"2026-04-27T13:55:29","guid":{"rendered":"https:\/\/life-peptide.com\/?post_type=product&#038;p=910"},"modified":"2026-07-22T10:57:40","modified_gmt":"2026-07-22T07:57:40","slug":"melanotan-2-10-mg","status":"publish","type":"product","link":"https:\/\/life-peptide.com\/cs\/product\/melanotan-2-10-mg\/","title":{"rendered":"Melanotan 2 (MT2) \/ 10 mg"},"content":{"rendered":"<p>Melanotan 2 (also known as Melanotan II or MT2) is one of the best-known research peptides for <strong>tanning and pigmentation studies<\/strong>. It is a synthetic <strong>analogue of \u03b1-melanocyte-stimulating hormone (\u03b1-MSH)<\/strong>, developed to investigate how melanocortin signalling regulates melanin production and the skin&#8217;s physiological response to ultraviolet (UV) exposure.<\/p>\n<p>Beyond pigmentation research, Melanotan 2 has played an important role in advancing our understanding of the melanocortin system. During early clinical investigations, researchers observed effects beyond skin pigmentation, leading to the later development of <a href=\"https:\/\/life-peptide.com\/cs\/product\/pt-141-10-mg\/\"><strong>PT-141 (Bremelanotide)<\/strong><\/a>, a more selective melanocortin peptide designed specifically for sexual function research.<\/p>\n<p>Today, Melanotan 2 remains one of the most extensively investigated peptides for pigmentation biology, melanocortin receptor signalling and neuroendocrine physiology.<\/p>\n<hr \/>\n<h4><strong>Why Melanotan 2 is widely investigated<\/strong><\/h4>\n<p>Published research has investigated Melanotan 2 in relation to:<\/p>\n<ul>\n<li>tanning research<\/li>\n<li>skin pigmentation<\/li>\n<li>melanin production<\/li>\n<li>melanogenesis<\/li>\n<li>UV-independent pigmentation<\/li>\n<li>melanocyte biology<\/li>\n<li>melanocortin receptor signalling<\/li>\n<li>appetite regulation<\/li>\n<li>neuroendocrine physiology<\/li>\n<\/ul>\n<p>Its broad receptor activity has made Melanotan 2 one of the foundational research peptides for understanding the melanocortin system.<\/p>\n<h4><strong>How Melanotan 2 promotes pigmentation<\/strong><\/h4>\n<p>Published research demonstrates that Melanotan 2 primarily <strong>activates the MC1 melanocortin receptor<\/strong>, which regulates melanin production within melanocytes.<\/p>\n<p>Research has explored its relationship with:<\/p>\n<p><strong>Melanin production<\/strong><\/p>\n<p>Activation of melanocytes and increased melanin synthesis, making Melanotan 2 one of the best-known peptides in pigmentation research.<\/p>\n<p><strong>UV response<\/strong><\/p>\n<p>Investigation of the relationship between melanocortin signalling, melanin production and the skin&#8217;s physiological response to ultraviolet exposure.<\/p>\n<p><strong>Pigmentation biology<\/strong><\/p>\n<p>Studies examining how melanocortin receptors regulate pigmentation across different skin types and experimental models.<\/p>\n<p>Because Melanotan 2 also activates other melanocortin receptors, researchers have investigated additional physiological pathways involving appetite regulation, energy balance and central nervous system signalling.<\/p>\n<h4><strong>Why Melanotan 2 became important beyond tanning research<\/strong><\/h4>\n<p>Although Melanotan 2 was originally developed for pigmentation research, investigators later discovered that melanocortin receptor activation also influenced central nervous system pathways involved in sexual behaviour.<\/p>\n<p>These findings ultimately led to the development of <a href=\"https:\/\/life-peptide.com\/cs\/product\/pt-141-10-mg\/\"><strong>PT-141 (Bremelanotide)<\/strong><\/a>, a more selective melanocortin peptide that focuses on sexual desire and arousal research rather than pigmentation.<\/p>\n<p>This makes Melanotan 2 one of the most influential peptides in the history of melanocortin research.<\/p>\n<hr \/>\n<h4><strong>Lidsk\u00fd a preklinick\u00fd v\u00fdzkum<\/strong><\/h4>\n<p>Melanotan 2 has been investigated extensively in both laboratory and human studies.<\/p>\n<p>Published research includes:<\/p>\n<ul>\n<li>tanning physiology<\/li>\n<li>pigmentation biology<\/li>\n<li>melanogenesis<\/li>\n<li>UV response<\/li>\n<li>melanocortin receptor pharmacology<\/li>\n<li>appetite regulation<\/li>\n<li>neuroendocrine signalling<\/li>\n<\/ul>\n<p>Although newer melanocortin analogues have since been developed for more specific applications, Melanotan 2 remains one of the principal research compounds for studying the melanocortin receptor family.<\/p>\n<h4><strong>How Melanotan 2 differs from related peptides<\/strong><\/h4>\n<table style=\"height: 142px;\" width=\"730\">\n<thead>\n<tr>\n<th>Research objective<\/th>\n<th>Recommended peptide<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Tanning &amp; pigmentation research<\/strong><\/td>\n<td><strong>Melanotan 2<\/strong><\/td>\n<\/tr>\n<tr>\n<td><strong>Sexual desire &amp; arousal research<\/strong><\/td>\n<td><a href=\"https:\/\/life-peptide.com\/cs\/product\/pt-141-10-mg\/\"><strong>PT-141 (Bremelanotide)<\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td><strong>Reproductive hormone regulation<\/strong><\/td>\n<td><a href=\"https:\/\/life-peptide.com\/cs\/product\/kisspeptin-10-5-mg\/\"><strong>Kisspeptin-10<\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td><strong>Social bonding &amp; neuroendocrine behaviour<\/strong><\/td>\n<td><a href=\"https:\/\/life-peptide.com\/cs\/product\/oxytocin-5-mg\/\"><strong>Oxytocin<\/strong><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Although Melanotan 2 and PT-141 share a common developmental history, they are now investigated for different research objectives. Melanotan 2 primarily focuses on pigmentation and melanocortin biology, whereas PT-141 investigates central pathways involved in sexual desire and arousal.<\/p>\n<h4><strong>Publikovan\u00e9 bezpe\u010dnostn\u00ed poznatky<\/strong><\/h4>\n<p>Published human studies have most commonly reported <strong>nausea, facial flushing, yawning and transient increases in skin pigmentation<\/strong>. Researchers have also observed increased pigmentation of freckles and existing moles, which has become an area of continued investigation. Current knowledge is based primarily on controlled clinical studies and experimental research, and long-term safety remains an active topic within the scientific literature.<\/p>\n<hr \/>\n<h4><strong>Vlastnosti produktu<\/strong><\/h4>\n<p>Aplikace: laboratorn\u00ed a analytick\u00fd v\u00fdzkum<br \/>\nPou\u017eit\u00ed omezen\u00e9: nen\u00ed ur\u010deno k lidsk\u00e9 spot\u0159eb\u011b; pro l\u00e9ka\u0159sk\u00e9, veterin\u00e1rn\u00ed ani kosmetick\u00e9 pou\u017eit\u00ed<br \/>\nVyrobeno v za\u0159\u00edzen\u00edch spl\u0148uj\u00edc\u00edch spr\u00e1vnou v\u00fdrobn\u00ed praxi (GMP) za p\u0159\u00edsn\u00fdch protokol\u016f kontroly kvality.<br \/>\nKa\u017ed\u00e1 \u0161ar\u017ee je po v\u00fdrob\u011b pe\u010dliv\u011b laboratorn\u011b testov\u00e1na (Certifik\u00e1t o anal\u00fdze najdete pod obr\u00e1zky produkt\u016f).<br \/>\nLyofilizov\u00e1no (su\u0161eno mrazem) pro maxim\u00e1ln\u00ed stabilitu a prodlou\u017eenou trvanlivost.<br \/>\nUzav\u0159eno ve steriln\u00edch lahvi\u010dk\u00e1ch, p\u0159ipraveno k rekonstituci.<br \/>\nPurity: \u2265 99% (HPLC)<br \/>\nVzhled: b\u00edl\u00fd lyofilizovan\u00fd pr\u00e1\u0161ek<br \/>\nMolekul\u00e1rn\u00ed vzorec: C<sub>50<\/sub>H<sub>69<\/sub>N<sub>15<\/sub>O<sub>9<\/sub><br \/>\nMolecular weight: 1024.2<br \/>\nCAS No: 121062-08-6<\/p>\n<p><strong>\u00dalo\u017ei\u0161t\u011b<\/strong>Neotev\u0159en\u00e9 lyofilizovan\u00e9 lahvi\u010dky jsou nejl\u00e9pe skladov\u00e1ny <strong>chlazen\u00e9 p\u0159i 2\u20138 \u00b0C<\/strong>, co\u017e je metoda skladov\u00e1n\u00ed potvrzen\u00e1 na\u0161\u00edm v\u00fdrobn\u00edm partnerem a vhodn\u00e1 a\u017e po dobu 24 m\u011bs\u00edc\u016f. Preferuje se chlazen\u00ed, proto\u017ee minimalizuje zbyte\u010dn\u00e9 cykly zmrazov\u00e1n\u00ed a rozmrazov\u00e1n\u00ed b\u011bhem b\u011b\u017en\u00e9 manipulace. Pokud je vy\u017eadov\u00e1no podstatn\u011b del\u0161\u00ed skladov\u00e1n\u00ed, lze zmrazen\u00e9 uchov\u00e1vat i neotev\u0159en\u00e9 lyofilizovan\u00e9 lahvi\u010dky. Po rekonstituci v\u017edy skladujte p\u0159i 2\u20138 \u00b0C a nezmrazujte.<\/p>\n<h4><strong>Rekonstituce a manipulace<\/strong><\/h4>\n<p>Melanotan 2 is supplied as a lyophilised vial and should be handled using standard peptide reconstitution procedures appropriate to the research setting. Must be reconstituted with <a href=\"https:\/\/life-peptide.com\/cs\/product\/bac-10-ml\/\">bakteriostatick\u00e1 voda<\/a> p\u0159ed pou\u017eit\u00edm. Pro zachov\u00e1n\u00ed struktur\u00e1ln\u00ed integrity p\u0159idejte zvolen\u00e9 rozpou\u0161t\u011bdlo pomalu po vnit\u0159n\u00ed st\u011bn\u011b lahvi\u010dky nam\u00edsto p\u0159\u00edmo na peptidov\u00fd pr\u00e1\u0161ek a vyhn\u011bte se prudk\u00e9mu prot\u0159ep\u00e1v\u00e1n\u00ed. Jemn\u00e9 krou\u017een\u00ed je obecn\u011b dosta\u010duj\u00edc\u00ed, jakmile se peptid zcela rozpust\u00ed. Standardn\u00ed laboratorn\u00ed postupy zahrnuj\u00ed tak\u00e9 ponech\u00e1n\u00ed chlazen\u00fdch lahvi\u010dek dos\u00e1hnout pokojov\u00e9 teploty p\u0159ed rekonstituc\u00ed, aby se minimalizovala kondenzace uvnit\u0159 lahvi\u010dky.<\/p>\n<p>Pro dal\u0161\u00ed pokyny k v\u00fdb\u011bru rozpou\u0161t\u011bdla, pl\u00e1nov\u00e1n\u00ed koncentrac\u00ed a skladov\u00e1n\u00ed viz \u00fapln\u00e9 <a href=\"https:\/\/life-peptide.com\/cs\/reconstitution-of-peptides\/\">Pr\u016fvodce rekonstituc\u00ed peptid\u016f<\/a> a <a href=\"https:\/\/life-peptide.com\/cs\/calculator\/\">Kalkula\u010dka rekonstituce<\/a>.<\/p>\n<hr \/>\n<h4><strong>Vybran\u00e9 v\u00fdzkumn\u00e9 reference<\/strong><\/h4>\n<ul>\n<li>Hadley ME. <em>Melanocortin Peptide Therapeutics: Historical Milestones, Clinical Studies and Commercialization, Peptides<\/em>, 2006<\/li>\n<\/ul>\n<p>A comprehensive review describing the development of Melanotan peptides, pigmentation research and the subsequent evolution of PT-141 from Melanotan 2.<\/p>\n<ul>\n<li>Dorr RT, et al. <em>Evaluation of Melanotan-II, a Superpotent Cyclic Melanotropic Peptide in a Pilot Phase I Clinical Study, Life Sciences<\/em>, 1996<\/li>\n<\/ul>\n<p>The first human clinical study evaluating Melanotan 2 and its effects on pigmentation.<\/p>\n<ul>\n<li>Habbema L, Halk AB, Neumann M, Bergman W. <em>Risks of Unregulated Use of Alpha-Melanocyte-Stimulating Hormone Analogues: A Review, International Journal of Dermatology<\/em>, 2017<\/li>\n<\/ul>\n<p>A review summarising the published evidence on Melanotan analogues, pigmentation effects and reported safety considerations.<\/p>\n<ul>\n<li>Wessells H, et al. <em>Melanocortin Receptor Agonists and Human Sexual Function, International Journal of Impotence Research,<\/em> 2000<\/li>\n<\/ul>\n<p>One of the early human studies showing central nervous system effects beyond pigmentation, contributing to the later development of PT-141.<\/p>\n<hr \/>\n<h4><strong>\u010casto kladen\u00e9 ot\u00e1zky<\/strong><\/h4>\n<p><strong>What is Melanotan 2?<\/strong><\/p>\n<p>Melanotan 2 is a synthetic analogue of \u03b1-melanocyte-stimulating hormone (\u03b1-MSH). It is one of the world&#8217;s most extensively investigated research peptides for tanning, pigmentation and melanocortin receptor biology.<\/p>\n<p><strong>How does Melanotan 2 promote pigmentation?<\/strong><\/p>\n<p>Melanotan 2 primarily activates the MC1 melanocortin receptor, which regulates melanin production within melanocytes. This has made it one of the leading research peptides for pigmentation and tanning studies.<\/p>\n<p><strong>How does Melanotan 2 differ from PT-141?<\/strong><\/p>\n<p>Although PT-141 was developed from Melanotan 2, the two peptides are investigated for different purposes. Melanotan 2 primarily focuses on pigmentation and melanocortin biology, while PT-141 is a more selective melanocortin peptide investigated mainly for sexual desire and arousal research.<\/p>\n<p><strong>Why is Melanotan 2 associated with appetite and sexual function research?<\/strong><\/p>\n<p>Melanotan 2 activates several melanocortin receptor subtypes in addition to MC1R, including receptors involved in appetite regulation and central nervous system signalling. Early studies unexpectedly observed effects on sexual function, which contributed to the later development of PT-141.<\/p>\n<p><strong>What research areas commonly investigate Melanotan 2?<\/strong><\/p>\n<p>Published research includes tanning physiology, skin pigmentation, melanogenesis, UV response, melanocortin receptor signalling, appetite regulation and neuroendocrine physiology.<\/p>\n<p><strong>How does Melanotan 2 differ from Melanotan 1 (Afamelanotide)?<\/strong><\/p>\n<p>Both peptides are derived from \u03b1-MSH, but Melanotan 2 activates multiple melanocortin receptor subtypes, whereas Afamelanotide is considerably more selective for MC1R. This broader receptor activity has made Melanotan 2 useful across a wider range of melanocortin research topics.<\/p>\n<p><strong>Je tento produkt ur\u010den k lidsk\u00e9mu pou\u017eit\u00ed?<\/strong><\/p>\n<p>No. Melanotan 2 supplied by LIFE Peptide is provided strictly for laboratory and analytical research. It is not intended for human consumption, diagnosis, treatment or prevention of disease. Any discussion of published studies summarises the current scientific literature relating to the Melanotan 2 molecule rather than the intended use of this product.<\/p>\n<hr \/>\n<h4><strong>Souvisej\u00edc\u00ed v\u00fdzkumn\u00fd kontext<\/strong><\/h4>\n<p>Melanotan 2 belongs to the broader <a href=\"\/cs\/category\/sexual-function-and-melanocortin-peptides\/\">Melanocortin and neuroendocrine peptide research category<\/a>, focusing on pigmentation pathways and central melanocortin signaling mechanisms.<br \/>\nResearchers exploring related melanocortin pathway models may also examine:<br \/>\n\u2022 <a href=\"https:\/\/life-peptide.com\/cs\/product\/pt-141-10-mg\/\">PT-141 (Bremelanotide)<\/a> \u2014 selective melanocortin receptor signaling research<br \/>\n\u2022 <a href=\"\/cs\/category\/cognitive-research-peptides\/\">Cognitive &amp; neuroresearch peptides<\/a> \u2014 CNS peptide signaling models<\/p>\n<p><strong>POZN\u00c1MKA<\/strong>Toto je pouze pro vzd\u011bl\u00e1vac\u00ed \u00fa\u010dely a nep\u0159edstavuje l\u00e9ka\u0159skou radu.<\/p>\n<p><strong>Z\u0159eknut\u00ed se odpov\u011bdnosti<\/strong><br \/>\nTento produkt je prod\u00e1v\u00e1n pouze pro v\u00fdzkumn\u00e9 \u00fa\u010dely. Nen\u00ed ur\u010den k diagnostice, l\u00e9\u010db\u011b, vyl\u00e9\u010den\u00ed nebo prevenci jak\u00fdchkoli onemocn\u011bn\u00ed. Kupuj\u00edc\u00ed p\u0159eb\u00edr\u00e1 plnou odpov\u011bdnost za \u0159\u00e1dnou manipulaci a pou\u017eit\u00ed.<\/p>","protected":false},"excerpt":{"rendered":"<p>Melanotan 2 is a synthetic melanocortin peptide studied for its interaction with pigmentation pathways, melanocortin receptor signaling, and neuroendocrine research models.<\/p>\n<p>||<\/p>\n<p>\u010cistota \u226599% | Doprava v r\u00e1mci EU od 5 \u20ac | Mo\u017enost volby dopravy zdarma | P\u0159ij\u00edm\u00e1me platby kartou<\/p>","protected":false},"featured_media":1240,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[23],"product_tag":[224,135,219,137,227,136,220,134,226,133,225],"class_list":["post-910","product","type-product","status-publish","has-post-thumbnail","product_cat-sexual-function-and-melanocortin-peptides","product_tag-hypothalamic-signaling","product_tag-melanocortin","product_tag-melanocortin-peptide","product_tag-melanogenesis","product_tag-melanogenesis-research","product_tag-mt2","product_tag-neuroendocrine-signaling","product_tag-pigmentation","product_tag-pigmentation-pathways","product_tag-tanning","product_tag--msh-analogue","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/product\/910","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/comments?post=910"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/media\/1240"}],"wp:attachment":[{"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/media?parent=910"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/product_brand?post=910"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/product_cat?post=910"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/life-peptide.com\/cs\/wp-json\/wp\/v2\/product_tag?post=910"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}