{"id":1289,"date":"2026-07-21T16:03:07","date_gmt":"2026-07-21T13:03:07","guid":{"rendered":"https:\/\/life-peptide.com\/?post_type=product&#038;p=1289"},"modified":"2026-07-21T16:03:09","modified_gmt":"2026-07-21T13:03:09","slug":"nad","status":"publish","type":"product","link":"https:\/\/life-peptide.com\/de\/product\/nad\/","title":{"rendered":"NAD+ \/ 500 mg"},"content":{"rendered":"<p>NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme found in every living cell.\u00a0Rather than acting as a signalling peptide or hormone, NAD+ functions as an essential electron carrier in hundreds of metabolic reactions, playing a central role in <strong>ATP production, mitochondrial function and cellular repair<\/strong>.<\/p>\n<p>Because NAD+ levels naturally decline with age and metabolic stress, it has become one of the most extensively investigated molecules in research on <strong>aging, energy metabolism and mitochondrial biology<\/strong>.<\/p>\n<hr \/>\n<h4><strong>Why NAD+ is widely investigated<\/strong><\/h4>\n<p>Published research has investigated NAD+ in relation to:<\/p>\n<ul>\n<li>cellular energy production<\/li>\n<li>mitochondriale Funktion<\/li>\n<li>gesundes Altern<\/li>\n<li>DNA repair<\/li>\n<li>oxidative stress<\/li>\n<li>metabolic health<\/li>\n<li>cognitive function<\/li>\n<li>muscle physiology<\/li>\n<li>sirtuin biology<\/li>\n<\/ul>\n<p>Unlike mitochondrial peptides, NAD+ serves as a fundamental metabolic cofactor required for normal cellular function across virtually every tissue.<\/p>\n<h4><strong>How NAD+ works<\/strong><\/h4>\n<p><strong>Cellular energy production<\/strong><\/p>\n<p>NAD+ plays a central role in converting nutrients into usable cellular energy.\u00a0It transfers electrons during glycolysis, the citric acid cycle and oxidative phosphorylation, allowing mitochondria to generate ATP efficiently.<\/p>\n<p><strong>Mitochondrial function<\/strong><\/p>\n<p>Healthy mitochondria depend on adequate NAD+ availability to support normal energy metabolism.\u00a0Research has investigated how declining NAD+ levels influence mitochondrial performance during aging and metabolic stress.<\/p>\n<p><strong>DNA repair<\/strong><\/p>\n<p>NAD+ serves as an essential substrate for enzymes involved in DNA repair, including PARPs, which respond to DNA damage by helping maintain genomic stability.<\/p>\n<p><strong>Sirtuin activation<\/strong><\/p>\n<p>NAD+ is also required by sirtuins, a family of enzymes involved in cellular stress responses, metabolism and healthy aging.\u00a0This relationship has made NAD+ a central focus of longevity research.<\/p>\n<hr \/>\n<h4><strong>Why NAD+ is different from mitochondrial peptides<\/strong><\/h4>\n<p>Although frequently discussed together, NAD+, SS-31 and MOTS-c investigate different aspects of mitochondrial biology.<\/p>\n<p><strong>NAD+<\/strong> supplies an essential coenzyme required for cellular energy metabolism.<br \/>\n<a href=\"https:\/\/life-peptide.com\/de\/product\/ss-31\/\"><strong>SS-31<\/strong><\/a> investigates mitochondrial membrane integrity and ATP production.<br \/>\n<a href=\"https:\/\/life-peptide.com\/de\/product\/mots-c-10-mg\/\"><strong>MOTS-c<\/strong> <\/a>studies metabolic signalling and adaptive cellular responses.<\/p>\n<p>Together, these represent complementary areas of cellular energy research rather than competing mechanisms.<\/p>\n<h4><strong>Menschliche und pr\u00e4klinische Forschung<\/strong><\/h4>\n<p>NAD+ has been investigated extensively in both laboratory and clinical settings.<\/p>\n<p>Current research explores its role in <strong>aging, metabolic disorders, neurodegeneration, cardiovascular physiology and mitochondrial disease<\/strong>. Much of this work also focuses on strategies to increase intracellular NAD+ through precursors such as NMN and nicotinamide riboside, reflecting the importance of NAD+ homeostasis in human physiology.<\/p>\n<p>Although the biological importance of NAD+ is well established, many therapeutic applications remain under active investigation.<\/p>\n<h4><strong>Ver\u00f6ffentlichte Sicherheitsbeobachtungen<\/strong><\/h4>\n<p>As a naturally occurring cellular coenzyme, NAD+ has been the subject of extensive biological research.<\/p>\n<p>Clinical investigations have generally reported favourable tolerability across a range of study designs, although research continues to evaluate optimal delivery methods, pharmacokinetics and potential applications in age-related disease.<\/p>\n<hr \/>\n<h3><strong>Produkteigenschaften<\/strong><\/h3>\n<p>Anwendung: Labor- und analytische Forschung<br \/>\nVerwendungseinschr\u00e4nkung: Nicht zum menschlichen Verzehr bestimmt; nicht f\u00fcr medizinische, veterin\u00e4rmedizinische oder kosmetische Zwecke<br \/>\nHergestellt in GMP-konformen Anlagen unter strengen Qualit\u00e4tskontrollprotokollen.<br \/>\nJede Charge wird nach der Produktion sorgf\u00e4ltig im Labor getestet (das Analysezertifikat finden Sie unter den Produktbildern).<br \/>\nGefriergetrocknet (lyophilisiert) f\u00fcr maximale Stabilit\u00e4t und l\u00e4ngere Haltbarkeit.<br \/>\nSteril in Fl\u00e4schchen abgef\u00fcllt, bereit zur Rekonstitution.<br \/>\nPurity: \u2265 99.47% , HPLC tested<br \/>\nAussehen: wei\u00dfes lyophilisiertes Pulver<br \/>\nMolecular formula:\u00a0C<sub>21<\/sub>H<sub>29<\/sub>N<sub>7<\/sub>O<sub>14<\/sub>P<sub>2<\/sub><sup>2+<\/sup><br \/>\nMolecular weight: 665.4<\/p>\n<p><strong>Speicher<\/strong>unge\u00f6ffnete gefriergetrocknete Vials werden am besten gelagert <strong>gek\u00fchlte Lagerung bei 2\u20138\u00b0C<\/strong>, welche die von unserem Fertigungspartner best\u00e4tigte Lagerungsmethode ist und sich f\u00fcr bis zu 24 Monate eignet. K\u00fchlung wird bevorzugt, da sie unn\u00f6tige Gefrier-Tau-Zyklen bei routinem\u00e4\u00dfiger Handhabung minimiert. Wenn eine deutlich l\u00e4ngerfristige Lagerung erforderlich ist, k\u00f6nnen auch unge\u00f6ffnete gefriergetrocknete Vials gefroren aufbewahrt werden. Nach der Rekonstitution immer bei 2\u20138 \u00b0C lagern und nicht einfrieren.<\/p>\n<h4><strong>Rekonstitution und Handhabung<\/strong><\/h4>\n<p>NAD+ is supplied as a lyophilised vial and should be handled using standard peptide reconstitution procedures appropriate to the research setting. Must be reconstituted with <a href=\"https:\/\/life-peptide.com\/de\/product\/bac-10-ml\/\">Bakteriostatisches Wasser<\/a> Vor Gebrauch. Um die strukturelle Integrit\u00e4t zu erhalten, geben Sie das gew\u00e4hlte L\u00f6sungsmittel langsam an der Innenwand des Fl\u00e4schchens hinzu und nicht direkt auf den Peptidkuchen, und vermeiden Sie kr\u00e4ftiges Sch\u00fctteln. Sanftes Schwenken ist im Allgemeinen ausreichend, sobald sich das Peptid vollst\u00e4ndig gel\u00f6st hat. Standardm\u00e4\u00dfige Laborpraxis beinhaltet auch, gek\u00fchlte Fl\u00e4schchen Raumtemperatur erreichen zu lassen, bevor sie rekonstituiert werden, um die Kondensation im Fl\u00e4schchen zu minimieren.<\/p>\n<p>F\u00fcr weitere Informationen zur L\u00f6sungsmittelauswahl, zur Konzentrationsplanung und zur Lagerung siehe das vollst\u00e4ndige <a href=\"https:\/\/life-peptide.com\/de\/rekonstitution-von-peptiden\/\">Leitfaden zur Peptidrekonstitution<\/a> und <a href=\"https:\/\/life-peptide.com\/de\/taschenrechner\/\">Rekonstitutionsrechner<\/a>.<\/p>\n<hr \/>\n<h4><strong>Ausgew\u00e4hlte Referenzen<\/strong><\/h4>\n<ul>\n<li>Covarrubias AJ, Perrone R, Grozio A, Verdin E. <em>NAD+ Metabolism and Its Roles in Cellular Processes During Ageing, Nature Reviews Molecular Cell Biology<\/em>, 2021.<\/li>\n<\/ul>\n<p>A comprehensive review of NAD+ biology, aging, metabolism and mitochondrial function.<\/p>\n<ul>\n<li>Yoshino J, Baur JA, Imai SI. <em>NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and Nicotinamide Riboside, Cell Metabolism<\/em>, 2018.<\/li>\n<\/ul>\n<p>A landmark review summarising NAD+ metabolism and strategies for restoring intracellular NAD+.<\/p>\n<ul>\n<li>Rajman L, Chwalek K, Sinclair DA.<em> Therapeutic Potential of NAD+ Boosting Molecules, Nature Reviews Drug Discovery<\/em>, 2018.<\/li>\n<\/ul>\n<p>A detailed overview of NAD+ biology and current therapeutic research.<\/p>\n<hr \/>\n<h4><strong>H\u00e4ufig gestellte Fragen<\/strong><\/h4>\n<p><strong>What is NAD+?<\/strong><\/p>\n<p>NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme essential for cellular energy production, mitochondrial function and DNA repair.<\/p>\n<p><strong>Is NAD+ a peptide?<\/strong><\/p>\n<p>No. NAD+ is not a peptide. It is a naturally occurring coenzyme found in every living cell and plays a central role in energy metabolism.<\/p>\n<p><strong>Why is NAD+ important for mitochondria?<\/strong><\/p>\n<p>NAD+ acts as an electron carrier during cellular respiration, allowing mitochondria to produce ATP efficiently and maintain normal energy metabolism.<\/p>\n<p><strong>How is NAD+ different from MOTS-c?<\/strong><\/p>\n<p>Although both investigate mitochondrial biology, NAD+ functions as an essential metabolic coenzyme, whereas MOTS-c acts as a mitochondrial signalling peptide that regulates cellular metabolism.<\/p>\n<p><strong>How is NAD+ different from SS-31?<\/strong><\/p>\n<p>SS-31 investigates the structural integrity of mitochondria by targeting the inner mitochondrial membrane, while NAD+ serves as a fundamental coenzyme required for cellular energy production.<\/p>\n<p><strong>Ist dieses Produkt f\u00fcr den menschlichen Gebrauch bestimmt?<\/strong><\/p>\n<p>No. NAD+ supplied by LIFE Peptide is intended strictly for laboratory and analytical research. It is not intended for human consumption, diagnosis, treatment or prevention of disease.<\/p>\n<hr \/>\n<h4><strong>Verwandter Forschungskontext<\/strong><\/h4>\n<p>NAD+ is frequently discussed alongside other research compounds investigating cellular energy, mitochondrial biology and healthy aging, although each targets distinct biological mechanisms.<\/p>\n<p><a href=\"https:\/\/life-peptide.com\/de\/product\/ss-31\/\">SS-31<\/a> (Elamipretide) \u2013 investigated for mitochondrial repair and cellular energy production.<br \/>\n<a href=\"https:\/\/life-peptide.com\/de\/product\/mots-c-10-mg\/\">MOTS-c<\/a> \u2013 studied for metabolic signalling and exercise adaptation.<br \/>\n<a href=\"https:\/\/life-peptide.com\/de\/product\/epitalon-10-mg\/\">Epitalon<\/a> \u2013 investigated for telomere biology and healthy aging research.<br \/>\n<a href=\"https:\/\/life-peptide.com\/de\/product\/ghk-cu-50-mg\/\">GHK-Cu<\/a> \u2013 studied for tissue regeneration and cellular repair.<br \/>\n<a href=\"https:\/\/life-peptide.com\/de\/product\/cjc-1295-with-dac\/\">CJC-1295 mit DAC<\/a> \u2013 investigated for sustained GH and IGF-1 signalling.<\/p>\n<p><strong>ANMERKUNG<\/strong>Dies dient ausschlie\u00dflich zu Bildungszwecken und stellt keine medizinische Beratung dar.<\/p>\n<p><strong>Haftungsausschluss<\/strong><br \/>\nDieses Produkt wird ausschlie\u00dflich zu Forschungszwecken verkauft. Es ist nicht dazu bestimmt, Krankheiten zu diagnostizieren, zu behandeln, zu heilen oder zu verhindern. Der K\u00e4ufer \u00fcbernimmt die volle Verantwortung f\u00fcr die ordnungsgem\u00e4\u00dfe Handhabung und Verwendung.<\/p>","protected":false},"excerpt":{"rendered":"<p>NAD+ (Nicotinamide Adenine Dinucleotide) 500 mg is a research-grade cellular coenzyme supplied in lyophilised form for laboratory use. As one of the most essential molecules in cellular metabolism, NAD+ is widely investigated for mitochondrial function, energy production, DNA repair and healthy aging research.<\/p>\n<p>||<\/p>\n<p>Purity \u226599% | EU Shipping from \u20ac5 | Free shipping upgrades available | Card payments accepted<\/p>","protected":false},"featured_media":1287,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[131],"product_tag":[361,329,383,325,384,382,364,380,381],"class_list":["post-1289","product","type-product","status-publish","has-post-thumbnail","product_cat-cellular-mitochondrial-research","product_tag-atp-production","product_tag-cellular-energy","product_tag-dna-repair","product_tag-healthy-aging","product_tag-longevity-research","product_tag-mitochondrial-function","product_tag-mitochondrial-research","product_tag-nad","product_tag-nicotinamide-adenine-dinucleotide","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/product\/1289","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/comments?post=1289"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/media\/1287"}],"wp:attachment":[{"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/media?parent=1289"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/product_brand?post=1289"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/product_cat?post=1289"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/product_tag?post=1289"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}