{"id":303,"date":"2026-02-18T16:12:56","date_gmt":"2026-02-18T14:12:56","guid":{"rendered":"http:\/\/example.test\/?post_type=product&#038;p=303"},"modified":"2026-05-28T16:48:55","modified_gmt":"2026-05-28T13:48:55","slug":"semaglutide-10-mg","status":"publish","type":"product","link":"https:\/\/life-peptide.com\/de\/product\/semaglutide-10-mg\/","title":{"rendered":"Semaglutid 10 mg"},"content":{"rendered":"<h4><strong>Semaglutide \u2013 1st generation single incretin agonist<\/strong><\/h4>\n<h4><strong>Product overview<\/strong><\/h4>\n<p>Semaglutide is a long-acting investigational peptide designed as a selective GLP-1 receptor agonist. As a single-pathway incretin compound, it serves as a foundational reference in metabolic research focused on glucose regulation, appetite signaling, and energy balance.<\/p>\n<p>Its extended half-life and receptor specificity make it widely used in experimental models examining sustained GLP-1 pathway activation. Compared to dual agonists such as <a href=\"https:\/\/life-peptide.com\/de\/product\/tirzepatide-10-mg\/\">Tirzepatid<\/a> and multi-receptor compounds like <a href=\"https:\/\/life-peptide.com\/de\/product\/retatrutide-10-mg\/\">Retatrutid<\/a>, Semaglutide represents a more targeted approach to incretin signaling, allowing researchers to isolate GLP-1\u2013mediated effects within complex metabolic systems.<\/p>\n<p>Because of this, it is frequently used as a baseline compound in comparative studies involving single, dual, and multi-receptor agonist strategies. For a broader comparison across incretin-based compounds, see the <a href=\"https:\/\/life-peptide.com\/de\/glp-1-metabolic-research-guide\/\">Leitfaden zur Stoffwechselforschung von GLP-1<\/a>.<\/p>\n<h4><strong>Research applications (investigational)<\/strong><\/h4>\n<p>Semaglutide has been investigated in preclinical and experimental settings for its involvement in:<\/p>\n<ul>\n<li>Selective GLP-1 receptor signaling pathways<\/li>\n<li>Glucose metabolism and insulin-related signaling dynamics<\/li>\n<li>Appetite regulation and satiety pathway modeling<\/li>\n<li>Energy balance and nutrient signaling mechanisms<\/li>\n<li>Gastrointestinal hormone signaling interactions<\/li>\n<li>Comparative analysis of single vs multi-receptor incretin activation<\/li>\n<\/ul>\n<p>These areas reflect ongoing scientific investigation into metabolic signaling systems rather than established applications.<\/p>\n<h4><strong>Product characteristics<\/strong><\/h4>\n<p>Purity: \u226599% (HPLC-tested)<br \/>\nAppearance: Lyophilized white\/off-white powder<br \/>\nMolecular formula: C<sub>187<\/sub>H<sub>291<\/sub>N<sub>45<\/sub>O<sub>59<\/sub><br \/>\nMolecular weight: 4113.64<br \/>\nSequence: His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-\u03b3-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly<br \/>\nStorage: store lyophilized powder at -20\u00b0C, protect from light and moisture. Reconstituted solution should be kept at 2\u20138\u00b0C and used within a short period.<\/p>\n<h4><strong>Why choose our Semaglutide?<\/strong><\/h4>\n<p>\u2265 99% purity verified by HPLC.<br \/>\nProduced in GMP-compliant facilities under strict QC protocols.<br \/>\nEach batch carefully lab tested after production (you can find Certificate of Analysis under product pictures).<br \/>\nFreeze-dried (lyophilized) for maximum stability and extended shelf life.<br \/>\nSealed in sterile vials, ready for reconstitution.<br \/>\nReconstitution: Must be reconstituted with <a href=\"https:\/\/life-peptide.com\/de\/product\/bac-10-ml\/\">bacteriostatic water<\/a> before use. GLP-1 class peptides are sometimes slow to dissolve and require very gentle reconstitution to avoid foaming or remaining slightly cloudy.<\/p>\n<h4>Selected research references<\/h4>\n<ul>\n<li>Wilding JPH et al. \u201c<em>Once-Weekly Semaglutide in Adults with Overweight or Obesity.\u201d New England Journal of Medicine<\/em>, 2021.<\/li>\n<li>Rubino D et al. <em>\u201cEffect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity.\u201d JAMA<\/em>, 2022.<\/li>\n<li>Davies M et al. <em>\u201cSemaglutide 2.4 mg once a week in adults with overweight or obesity.\u201d Nature Reviews Endocrinology<\/em>, 2021.<\/li>\n<li>Lau J et al. <em>\u201cDiscovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide.\u201d Journal of Medicinal Chemistry<\/em>, 2015.<\/li>\n<li>ClinicalTrials.gov Identifier: NCT03548935 \u2014 <em>Semaglutide research in obesity and metabolic regulation models.<\/em><\/li>\n<\/ul>\n<h4><strong>Related research context<\/strong><\/h4>\n<p>Semaglutide belongs to the GLP-1 receptor agonist class within incretin-based metabolic research. For mechanistic comparison with dual and triple agonists, see our <strong><a href=\"http:\/\/example.test\/glp-1-metabolic-research-guide\/\" target=\"_blank\" rel=\"noopener\">Leitfaden zur Stoffwechselforschung von GLP-1<\/a>.<\/strong><\/p>\n<p>Browse all compounds in the <a title=\"Metabolic research category.\" href=\"\/de\/product-category\/metabolic-research\/\"><strong>Metabolic research category.<\/strong><\/a><\/p>\n<p>For pathway comparison:<\/p>\n<ul data-start=\"2633\" data-end=\"2702\">\n<li data-start=\"2633\" data-end=\"2671\">\n<p data-start=\"2635\" data-end=\"2671\">Dual agonists: \u00a0<a href=\"http:\/\/example.test\/product\/tirzepatide-10-mg\/\" target=\"_blank\" rel=\"noopener\">Tirzepatide (GLP-1\/GIP)<\/a><\/p>\n<\/li>\n<li data-start=\"2672\" data-end=\"2702\">\n<p data-start=\"2674\" data-end=\"2702\">Triple agonists: <a href=\"http:\/\/example.test\/product\/retatrutide-10-mg\/\" target=\"_blank\" rel=\"noopener\">Retatrutide (GLP-1\/GIP\/glucagon)<\/a><\/p>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>NOTE: <\/strong>This is for educational reference only and does not constitute medical advice.<\/p>\n<p><strong>Disclaimer:<\/strong><br \/>\nThis product is sold for research purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. Buyer assumes full responsibility for proper handling and use.<\/p>","protected":false},"excerpt":{"rendered":"<p>Semaglutide is a synthetic GLP-1 receptor agonist studied for interaction with incretin signaling pathways in metabolic research models.<\/p>\n<p>||<\/p>\n<p>HPLC Purity \u226599% | Lyophilized | Research grade | EU-based supply | Free EU shipping over \u20ac100<\/p>","protected":false},"featured_media":307,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[19],"product_tag":[249,254,248,253,139,255,247,256,246],"class_list":["post-303","product","type-product","status-publish","has-post-thumbnail","product_cat-metabolic-research-peptides","product_tag-appetite-pathways","product_tag-blood-glucose-research","product_tag-energy-balance","product_tag-glp-1-agonist","product_tag-glp-1-research","product_tag-incretin-signaling","product_tag-metabolic-peptide","product_tag-satiety-pathways","product_tag-weight-loss-peptide","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/product\/303","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/comments?post=303"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/media\/307"}],"wp:attachment":[{"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/media?parent=303"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/product_brand?post=303"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/product_cat?post=303"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/life-peptide.com\/de\/wp-json\/wp\/v2\/product_tag?post=303"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}