{"id":1278,"date":"2026-07-20T17:00:09","date_gmt":"2026-07-20T14:00:09","guid":{"rendered":"https:\/\/life-peptide.com\/?post_type=product&#038;p=1278"},"modified":"2026-07-21T11:14:51","modified_gmt":"2026-07-21T08:14:51","slug":"ss-31","status":"publish","type":"product","link":"https:\/\/life-peptide.com\/es\/product\/ss-31\/","title":{"rendered":"SS-31 \/ 10 mg"},"content":{"rendered":"<p>SS-31, also known as <strong>Elamipretide, MTP-131 or Bendavia<\/strong>, is a synthetic <strong>mitochondria-targeting tetrapeptide<\/strong>.<\/p>\n<p>Unlike most peptides, SS-31 does not primarily interact with a cell-surface receptor. Instead, it rapidly enters cells and selectively accumulates within mitochondria, where it binds cardiolipin, a phospholipid unique to the inner mitochondrial membrane.<\/p>\n<p>Because cardiolipin is essential for maintaining mitochondrial architecture and efficient ATP production, SS-31 has become one of the leading investigational peptides for research into <strong>mitochondrial dysfunction, oxidative stress and cellular energy metabolism<\/strong>.<\/p>\n<hr \/>\n<h4><strong>Why SS-31 is widely investigated<\/strong><\/h4>\n<p>Published research has investigated SS-31 in relation to:<\/p>\n<ul>\n<li><strong>mitochondrial repair<\/strong><\/li>\n<li><strong>cellular energy production<\/strong><\/li>\n<li><strong>ATP synthesis<\/strong><\/li>\n<li><strong>oxidative stress<\/strong><\/li>\n<li><strong>muscle physiology<\/strong><\/li>\n<li><strong>healthy aging<\/strong><\/li>\n<li><strong>cardiovascular research<\/strong><\/li>\n<li><strong>neurodegeneration<\/strong><\/li>\n<li><strong>mitochondrial disease<\/strong><\/li>\n<\/ul>\n<p>Unlike metabolic peptides that regulate cellular signalling, SS-31 directly targets the physical structure of mitochondria, making it unique among modern research peptides.<\/p>\n<h4><strong>How SS-31 works<\/strong><\/h4>\n<p><strong>Cardiolipin stabilisation<\/strong><\/p>\n<p>SS-31 selectively binds cardiolipin, an essential phospholipid located within the inner mitochondrial membrane.<\/p>\n<p>Cardiolipin plays a critical role in maintaining mitochondrial cristae structure and supporting the electron transport chain. Under conditions of oxidative stress, cardiolipin becomes damaged, reducing mitochondrial efficiency. Published research suggests SS-31 helps stabilise this membrane environment and preserve mitochondrial function.<\/p>\n<p><strong>Cellular energy production<\/strong><\/p>\n<p>By preserving mitochondrial structure, SS-31 has been investigated for improving the efficiency of oxidative phosphorylation and ATP generation.\u00a0Rather than stimulating mitochondria to produce more energy, SS-31 appears to help dysfunctional mitochondria produce energy more efficiently.<\/p>\n<p><strong>Oxidative stress<\/strong><\/p>\n<p>Numerous preclinical studies have investigated SS-31 for reducing mitochondrial reactive oxygen species (ROS) and limiting oxidative damage associated with impaired mitochondrial function.<\/p>\n<p><strong>Tissue protection<\/strong><\/p>\n<p>Because mitochondria influence virtually every organ system, SS-31 has been investigated across cardiovascular, neurological, renal and skeletal muscle research, making it one of the broadest mitochondrial peptides currently available.<\/p>\n<hr \/>\n<h4><strong>Why SS-31 is different from other mitochondrial peptides<\/strong><\/h4>\n<p>Not all mitochondrial peptides investigate the same biology.<\/p>\n<p><a href=\"https:\/\/life-peptide.com\/es\/product\/mots-c-10-mg\/\">MOTS-c<\/a> investigates how cells regulate energy metabolism by activating adaptive metabolic signalling pathways.<\/p>\n<p><strong>SS-31<\/strong> investigates how mitochondria physically produce energy by stabilising the inner mitochondrial membrane and preserving electron transport chain function.<\/p>\n<p>Rather than changing metabolic signalling, SS-31 focuses on maintaining the mitochondrial machinery itself.<\/p>\n<p>This distinction has made SS-31 one of the most important investigational peptides for mitochondrial biology and healthy aging research.<\/p>\n<h4><strong>Investigaci\u00f3n humana y precl\u00ednica<\/strong><\/h4>\n<p>SS-31 has progressed further into clinical development than many research peptides.<\/p>\n<p>Human studies have investigated SS-31 in <strong>primary mitochondrial disease, Barth syndrome, heart failure, kidney injury and ophthalmic disorders<\/strong>, while extensive preclinical research has explored its effects on skeletal muscle, neurodegeneration, ischemia-reperfusion injury and age-related mitochondrial dysfunction.<\/p>\n<p>Although clinical results have varied by indication, SS-31 remains one of the best-characterised mitochondria-targeting peptides currently under investigation.<\/p>\n<h4><strong>Published safety observations<\/strong><\/h4>\n<p>SS-31 has undergone multiple clinical studies across several disease areas.<\/p>\n<p>Published trials have generally reported favourable tolerability, with adverse events typically mild to moderate. Clinical efficacy has varied depending on the condition under investigation, highlighting the complexity of mitochondrial diseases and the need for continued research.<\/p>\n<hr \/>\n<h3><strong>Caracter\u00edsticas del producto<\/strong><\/h3>\n<p>Aplicaci\u00f3n: investigaci\u00f3n de laboratorio y an\u00e1lisis<br \/>\nUso restringido: no apto para consumo humano; no apto para uso m\u00e9dico, veterinario o cosm\u00e9tico<br \/>\nProducido en instalaciones que cumplen con GMP bajo estrictos protocolos de control de calidad.<br \/>\nCada lote se somete a pruebas de laboratorio exhaustivas despu\u00e9s de la producci\u00f3n (puede encontrar el Certificado de An\u00e1lisis debajo de las im\u00e1genes del producto).<br \/>\nLiofilizado (liofilizado) para m\u00e1xima estabilidad y vida \u00fatil prolongada.<br \/>\nSellado en viales est\u00e9riles, listo para la reconstituci\u00f3n.<br \/>\nPurity: \u2265 99.88% , HPLC tested.<br \/>\nApariencia: polvo blanco liofilizado<br \/>\nF\u00f3rmula molecular: C<sub>32<\/sub>H<sub>49<\/sub>N<sub>9<\/sub>O<sub>5<\/sub><br \/>\nMolecular weight: 639.79<\/p>\n<p><strong>Almacenamiento<\/strong>: los viales liofilizados sin abrir se almacenan mejor <strong>refrigerar a 2\u20138 \u00b0C<\/strong>, que es el m\u00e9todo de almacenamiento confirmado por nuestro socio de fabricaci\u00f3n y adecuado para hasta 24 meses. Se prefiere la refrigeraci\u00f3n porque minimiza los ciclos innecesarios de congelaci\u00f3n y descongelaci\u00f3n durante la manipulaci\u00f3n rutinaria. Si se requiere un almacenamiento a m\u00e1s largo plazo, los viales liofilizados sin abrir tambi\u00e9n pueden mantenerse congelados. Una vez reconstituidos, almacene siempre a 2\u20138 \u00b0C y no congele.<\/p>\n<h4><strong>Reconstituci\u00f3n y manipulaci\u00f3n<\/strong><\/h4>\n<p>SS-31 is supplied as a lyophilised vial and should be handled using standard peptide reconstitution procedures appropriate to the research setting. Must be reconstituted with <a href=\"https:\/\/life-peptide.com\/es\/product\/bac-10-ml\/\">agua bacteriost\u00e1tica<\/a> antes de usar. Para ayudar a preservar la integridad estructural, agregue el disolvente elegido lentamente contra la pared interior del vial en lugar de directamente sobre el p\u00e9ptido en polvo, y evite agitar vigorosamente. La agitaci\u00f3n suave suele ser suficiente una vez que el p\u00e9ptido se ha disuelto por completo. La pr\u00e1ctica est\u00e1ndar de laboratorio tambi\u00e9n incluye permitir que los viales refrigerados alcancen la temperatura ambiente antes de la reconstituci\u00f3n para minimizar la condensaci\u00f3n dentro del vial.<\/p>\n<p>Para otras gu\u00edas sobre selecci\u00f3n de solventes, planificaci\u00f3n de concentraciones y almacenamiento, consulte el completo <a href=\"https:\/\/life-peptide.com\/es\/reconstitution-of-peptides\/\">Gu\u00eda de Reconstituci\u00f3n de P\u00e9ptidos<\/a> y <a href=\"https:\/\/life-peptide.com\/es\/calculator\/\">Calculadora de Reconstituci\u00f3n<\/a>.<\/p>\n<hr \/>\n<h4><strong>Referencias de investigaci\u00f3n seleccionadas<\/strong><\/h4>\n<ul>\n<li>Wang Y, et al. <em>Elamipretide: A Review of Its Structure, Mechanism of Action, and Therapeutic Potential, Life<\/em>, 2025<\/li>\n<\/ul>\n<p>A comprehensive review covering SS-31&#8217;s mechanism, cardiolipin binding, mitochondrial bioenergetics and clinical development.<\/p>\n<ul>\n<li>Liu Y, et al. <em>Application Research of Novel Peptide Mitochondrial-Targeted Antioxidant SS-31 in Mitigating Mitochondrial Dysfunction, Redox Report<\/em>, 2024<\/li>\n<\/ul>\n<p>A detailed review of SS-31&#8217;s mechanisms and analysis of 18 clinical trials across mitochondrial disorders and related diseases.<\/p>\n<ul>\n<li>Chatfield KC, et al. <em>Elamipretide Improves Mitochondrial Function in the Failing Human Heart, JACC: Basic to Translational Science<\/em>, 2019<\/li>\n<\/ul>\n<p>Demonstrates improvements in mitochondrial function in human heart tissue and supports SS-31&#8217;s cardiolipin-targeted mechanism.<\/p>\n<hr \/>\n<h4><strong>Preguntas Frecuentes<\/strong><\/h4>\n<p><strong>What is SS-31?<\/strong><\/p>\n<p>SS-31 (Elamipretide) is a synthetic tetrapeptide that selectively targets mitochondria by binding cardiolipin within the inner mitochondrial membrane. It is widely investigated for mitochondrial repair, cellular energy production and healthy aging research.<\/p>\n<p><strong>Why is SS-31 called a mitochondrial repair peptide?<\/strong><\/p>\n<p>Unlike most peptides that activate cell-surface receptors, SS-31 directly targets the inner mitochondrial membrane. Research suggests it helps preserve mitochondrial structure, improve bioenergetics and reduce oxidative stress in dysfunctional mitochondria.<\/p>\n<p><strong>How is SS-31 different from MOTS-c?<\/strong><\/p>\n<p>Both investigate mitochondrial biology, but MOTS-c primarily regulates metabolic signalling, whereas SS-31 focuses on the physical integrity and efficiency of the mitochondrial energy-producing machinery. They investigate complementary aspects of mitochondrial function.<\/p>\n<p><strong>What research areas commonly investigate SS-31?<\/strong><\/p>\n<p>Current research includes mitochondrial disease, cardiovascular physiology, skeletal muscle function, neurodegeneration, kidney injury, metabolic disorders and healthy aging.<\/p>\n<p><strong>Is SS-31 one of the more clinically studied peptides?<\/strong><\/p>\n<p>Yes. Compared with many research peptides, SS-31 has advanced into multiple Phase 2 and Phase 3 clinical programmes across several mitochondrial-related diseases, making it one of the best-studied mitochondrial peptides currently available.<\/p>\n<p><strong>\u00bfEst\u00e1 este producto destinado al uso humano?<\/strong><\/p>\n<p>No. SS-31 supplied by LIFE Peptide is intended strictly for laboratory and analytical research. It is not intended for human consumption, diagnosis, treatment or prevention of disease.<\/p>\n<hr \/>\n<h4><strong>Contexto de investigaci\u00f3n relacionado<\/strong><\/h4>\n<p>SS-31 is frequently discussed alongside other research peptides investigating cellular energy, recovery and healthy aging, although each targets a different level of cellular physiology.<\/p>\n<p><a href=\"https:\/\/life-peptide.com\/es\/product\/mots-c-10-mg\/\"><strong>MOTS-c<\/strong><\/a> \u2013 investigated for metabolic signalling, exercise adaptation and mitochondrial communication.<br \/>\n<a href=\"https:\/\/life-peptide.com\/es\/product\/epitalon-10-mg\/\"><strong>Epitalon<\/strong> <\/a>\u2013 studied for telomere biology, circadian regulation and healthy aging.<br \/>\n<a href=\"https:\/\/life-peptide.com\/es\/product\/ghk-cu-50-mg\/\"><strong>GHK-Cu<\/strong><\/a> \u2013 investigated for tissue repair, extracellular matrix remodelling and regenerative biology.<br \/>\n<a href=\"https:\/\/life-peptide.com\/es\/product\/ara-290-16-mg\/\"><strong>ARA-290<\/strong><\/a> \u2013 focuses on innate tissue repair, inflammatory signalling and nerve regeneration.<br \/>\n<a href=\"https:\/\/life-peptide.com\/es\/product\/cjc-1295-with-dac\/\"><strong>CJC-1295 with DAC<\/strong> <\/a>\u2013 investigated for sustained growth hormone and IGF-1 signalling that supports anabolic physiology.<\/p>\n<p>Although these peptides are frequently associated with longevity and recovery research, SS-31 stands apart through its direct action on mitochondrial structure and bioenergetics rather than hormonal or metabolic signalling.<\/p>\n<p><strong>NOTA<\/strong>: Esto es solo para fines de referencia educativa y no constituye asesoramiento m\u00e9dico.<\/p>\n<p><strong>Descargo de responsabilidad<\/strong><br \/>\nEste producto se vende \u00fanicamente para fines de investigaci\u00f3n. No est\u00e1 destinado a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. El comprador asume toda la responsabilidad por su manipulaci\u00f3n y uso adecuados.<\/p>","protected":false},"excerpt":{"rendered":"<p>SS-31 (Elamipretide) 10 mg is a research-grade mitochondrial repair peptide supplied in lyophilised form for laboratory use. It is one of the most extensively investigated peptides for mitochondrial function, cellular energy production and healthy aging, with clinical research spanning cardiovascular disease, mitochondrial disorders, muscle physiology and neurodegeneration.<\/p>\n<p>||<\/p>\n<p>Purity \u226599% | EU Shipping from \u20ac5 | Free shipping upgrades available | Card payments accepted<\/p>","protected":false},"featured_media":1275,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[131],"product_tag":[361,362,329,359,357,323,360,364,363],"class_list":["post-1278","product","type-product","status-publish","has-post-thumbnail","product_cat-cellular-mitochondrial-research","product_tag-atp-production","product_tag-cardiolipin","product_tag-cellular-energy","product_tag-elamipretide","product_tag-healthy-aging-peptide","product_tag-mitochondrial-peptide","product_tag-mitochondrial-repair","product_tag-mitochondrial-research","product_tag-oxidative-stress","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/product\/1278","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/comments?post=1278"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/media\/1275"}],"wp:attachment":[{"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/media?parent=1278"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/product_brand?post=1278"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/product_cat?post=1278"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/product_tag?post=1278"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}