{"id":1289,"date":"2026-07-21T16:03:07","date_gmt":"2026-07-21T13:03:07","guid":{"rendered":"https:\/\/life-peptide.com\/?post_type=product&#038;p=1289"},"modified":"2026-07-21T16:03:09","modified_gmt":"2026-07-21T13:03:09","slug":"nad","status":"publish","type":"product","link":"https:\/\/life-peptide.com\/es\/product\/nad\/","title":{"rendered":"NAD+ \/ 500 mg"},"content":{"rendered":"<p>NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme found in every living cell.\u00a0Rather than acting as a signalling peptide or hormone, NAD+ functions as an essential electron carrier in hundreds of metabolic reactions, playing a central role in <strong>ATP production, mitochondrial function and cellular repair<\/strong>.<\/p>\n<p>Because NAD+ levels naturally decline with age and metabolic stress, it has become one of the most extensively investigated molecules in research on <strong>aging, energy metabolism and mitochondrial biology<\/strong>.<\/p>\n<hr \/>\n<h4><strong>Why NAD+ is widely investigated<\/strong><\/h4>\n<p>Published research has investigated NAD+ in relation to:<\/p>\n<ul>\n<li>cellular energy production<\/li>\n<li>mitochondrial function<\/li>\n<li>healthy aging<\/li>\n<li>DNA repair<\/li>\n<li>oxidative stress<\/li>\n<li>metabolic health<\/li>\n<li>cognitive function<\/li>\n<li>muscle physiology<\/li>\n<li>sirtuin biology<\/li>\n<\/ul>\n<p>Unlike mitochondrial peptides, NAD+ serves as a fundamental metabolic cofactor required for normal cellular function across virtually every tissue.<\/p>\n<h4><strong>How NAD+ works<\/strong><\/h4>\n<p><strong>Cellular energy production<\/strong><\/p>\n<p>NAD+ plays a central role in converting nutrients into usable cellular energy.\u00a0It transfers electrons during glycolysis, the citric acid cycle and oxidative phosphorylation, allowing mitochondria to generate ATP efficiently.<\/p>\n<p><strong>Mitochondrial function<\/strong><\/p>\n<p>Healthy mitochondria depend on adequate NAD+ availability to support normal energy metabolism.\u00a0Research has investigated how declining NAD+ levels influence mitochondrial performance during aging and metabolic stress.<\/p>\n<p><strong>DNA repair<\/strong><\/p>\n<p>NAD+ serves as an essential substrate for enzymes involved in DNA repair, including PARPs, which respond to DNA damage by helping maintain genomic stability.<\/p>\n<p><strong>Sirtuin activation<\/strong><\/p>\n<p>NAD+ is also required by sirtuins, a family of enzymes involved in cellular stress responses, metabolism and healthy aging.\u00a0This relationship has made NAD+ a central focus of longevity research.<\/p>\n<hr \/>\n<h4><strong>Why NAD+ is different from mitochondrial peptides<\/strong><\/h4>\n<p>Although frequently discussed together, NAD+, SS-31 and MOTS-c investigate different aspects of mitochondrial biology.<\/p>\n<p><strong>NAD+<\/strong> supplies an essential coenzyme required for cellular energy metabolism.<br \/>\n<a href=\"https:\/\/life-peptide.com\/es\/product\/ss-31\/\"><strong>SS-31<\/strong><\/a> investigates mitochondrial membrane integrity and ATP production.<br \/>\n<a href=\"https:\/\/life-peptide.com\/es\/product\/mots-c-10-mg\/\"><strong>MOTS-c<\/strong> <\/a>studies metabolic signalling and adaptive cellular responses.<\/p>\n<p>Together, these represent complementary areas of cellular energy research rather than competing mechanisms.<\/p>\n<h4><strong>Investigaci\u00f3n humana y precl\u00ednica<\/strong><\/h4>\n<p>NAD+ has been investigated extensively in both laboratory and clinical settings.<\/p>\n<p>Current research explores its role in <strong>aging, metabolic disorders, neurodegeneration, cardiovascular physiology and mitochondrial disease<\/strong>. Much of this work also focuses on strategies to increase intracellular NAD+ through precursors such as NMN and nicotinamide riboside, reflecting the importance of NAD+ homeostasis in human physiology.<\/p>\n<p>Although the biological importance of NAD+ is well established, many therapeutic applications remain under active investigation.<\/p>\n<h4><strong>Published safety observations<\/strong><\/h4>\n<p>As a naturally occurring cellular coenzyme, NAD+ has been the subject of extensive biological research.<\/p>\n<p>Clinical investigations have generally reported favourable tolerability across a range of study designs, although research continues to evaluate optimal delivery methods, pharmacokinetics and potential applications in age-related disease.<\/p>\n<hr \/>\n<h3><strong>Caracter\u00edsticas del producto<\/strong><\/h3>\n<p>Aplicaci\u00f3n: investigaci\u00f3n de laboratorio y an\u00e1lisis<br \/>\nUso restringido: no apto para consumo humano; no apto para uso m\u00e9dico, veterinario o cosm\u00e9tico<br \/>\nProducido en instalaciones que cumplen con GMP bajo estrictos protocolos de control de calidad.<br \/>\nCada lote se somete a pruebas de laboratorio exhaustivas despu\u00e9s de la producci\u00f3n (puede encontrar el Certificado de An\u00e1lisis debajo de las im\u00e1genes del producto).<br \/>\nLiofilizado (liofilizado) para m\u00e1xima estabilidad y vida \u00fatil prolongada.<br \/>\nSellado en viales est\u00e9riles, listo para la reconstituci\u00f3n.<br \/>\nPurity: \u2265 99.47% , HPLC tested<br \/>\nApariencia: polvo blanco liofilizado<br \/>\nMolecular formula:\u00a0C<sub>21<\/sub>H<sub>29<\/sub>N<sub>7<\/sub>O<sub>14<\/sub>P<sub>2<\/sub><sup>2+<\/sup><br \/>\nMolecular weight: 665.4<\/p>\n<p><strong>Almacenamiento<\/strong>: los viales liofilizados sin abrir se almacenan mejor <strong>refrigerar a 2\u20138 \u00b0C<\/strong>, que es el m\u00e9todo de almacenamiento confirmado por nuestro socio de fabricaci\u00f3n y adecuado para hasta 24 meses. Se prefiere la refrigeraci\u00f3n porque minimiza los ciclos innecesarios de congelaci\u00f3n y descongelaci\u00f3n durante la manipulaci\u00f3n rutinaria. Si se requiere un almacenamiento a m\u00e1s largo plazo, los viales liofilizados sin abrir tambi\u00e9n pueden mantenerse congelados. Una vez reconstituidos, almacene siempre a 2\u20138 \u00b0C y no congele.<\/p>\n<h4><strong>Reconstituci\u00f3n y manipulaci\u00f3n<\/strong><\/h4>\n<p>NAD+ is supplied as a lyophilised vial and should be handled using standard peptide reconstitution procedures appropriate to the research setting. Must be reconstituted with <a href=\"https:\/\/life-peptide.com\/es\/product\/bac-10-ml\/\">agua bacteriost\u00e1tica<\/a> antes de usar. Para ayudar a preservar la integridad estructural, agregue el disolvente elegido lentamente contra la pared interior del vial en lugar de directamente sobre el p\u00e9ptido en polvo, y evite agitar vigorosamente. La agitaci\u00f3n suave suele ser suficiente una vez que el p\u00e9ptido se ha disuelto por completo. La pr\u00e1ctica est\u00e1ndar de laboratorio tambi\u00e9n incluye permitir que los viales refrigerados alcancen la temperatura ambiente antes de la reconstituci\u00f3n para minimizar la condensaci\u00f3n dentro del vial.<\/p>\n<p>Para otras gu\u00edas sobre selecci\u00f3n de solventes, planificaci\u00f3n de concentraciones y almacenamiento, consulte el completo <a href=\"https:\/\/life-peptide.com\/es\/reconstitution-of-peptides\/\">Gu\u00eda de Reconstituci\u00f3n de P\u00e9ptidos<\/a> y <a href=\"https:\/\/life-peptide.com\/es\/calculator\/\">Calculadora de Reconstituci\u00f3n<\/a>.<\/p>\n<hr \/>\n<h4><strong>Referencias de investigaci\u00f3n seleccionadas<\/strong><\/h4>\n<ul>\n<li>Covarrubias AJ, Perrone R, Grozio A, Verdin E. <em>NAD+ Metabolism and Its Roles in Cellular Processes During Ageing, Nature Reviews Molecular Cell Biology<\/em>, 2021.<\/li>\n<\/ul>\n<p>A comprehensive review of NAD+ biology, aging, metabolism and mitochondrial function.<\/p>\n<ul>\n<li>Yoshino J, Baur JA, Imai SI. <em>NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and Nicotinamide Riboside, Cell Metabolism<\/em>, 2018.<\/li>\n<\/ul>\n<p>A landmark review summarising NAD+ metabolism and strategies for restoring intracellular NAD+.<\/p>\n<ul>\n<li>Rajman L, Chwalek K, Sinclair DA.<em> Therapeutic Potential of NAD+ Boosting Molecules, Nature Reviews Drug Discovery<\/em>, 2018.<\/li>\n<\/ul>\n<p>A detailed overview of NAD+ biology and current therapeutic research.<\/p>\n<hr \/>\n<h4><strong>Preguntas Frecuentes<\/strong><\/h4>\n<p><strong>What is NAD+?<\/strong><\/p>\n<p>NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme essential for cellular energy production, mitochondrial function and DNA repair.<\/p>\n<p><strong>Is NAD+ a peptide?<\/strong><\/p>\n<p>No. NAD+ is not a peptide. It is a naturally occurring coenzyme found in every living cell and plays a central role in energy metabolism.<\/p>\n<p><strong>Why is NAD+ important for mitochondria?<\/strong><\/p>\n<p>NAD+ acts as an electron carrier during cellular respiration, allowing mitochondria to produce ATP efficiently and maintain normal energy metabolism.<\/p>\n<p><strong>How is NAD+ different from MOTS-c?<\/strong><\/p>\n<p>Although both investigate mitochondrial biology, NAD+ functions as an essential metabolic coenzyme, whereas MOTS-c acts as a mitochondrial signalling peptide that regulates cellular metabolism.<\/p>\n<p><strong>How is NAD+ different from SS-31?<\/strong><\/p>\n<p>SS-31 investigates the structural integrity of mitochondria by targeting the inner mitochondrial membrane, while NAD+ serves as a fundamental coenzyme required for cellular energy production.<\/p>\n<p><strong>\u00bfEst\u00e1 este producto destinado al uso humano?<\/strong><\/p>\n<p>No. NAD+ supplied by LIFE Peptide is intended strictly for laboratory and analytical research. It is not intended for human consumption, diagnosis, treatment or prevention of disease.<\/p>\n<hr \/>\n<h4><strong>Contexto de investigaci\u00f3n relacionado<\/strong><\/h4>\n<p>NAD+ is frequently discussed alongside other research compounds investigating cellular energy, mitochondrial biology and healthy aging, although each targets distinct biological mechanisms.<\/p>\n<p><a href=\"https:\/\/life-peptide.com\/es\/product\/ss-31\/\">SS-31<\/a> (Elamipretide) \u2013 investigated for mitochondrial repair and cellular energy production.<br \/>\n<a href=\"https:\/\/life-peptide.com\/es\/product\/mots-c-10-mg\/\">MOTS-c<\/a> \u2013 studied for metabolic signalling and exercise adaptation.<br \/>\n<a href=\"https:\/\/life-peptide.com\/es\/product\/epitalon-10-mg\/\">Epitalon<\/a> \u2013 investigated for telomere biology and healthy aging research.<br \/>\n<a href=\"https:\/\/life-peptide.com\/es\/product\/ghk-cu-50-mg\/\">GHK-Cu<\/a> \u2013 studied for tissue regeneration and cellular repair.<br \/>\n<a href=\"https:\/\/life-peptide.com\/es\/product\/cjc-1295-with-dac\/\">CJC-1295 with DAC<\/a> \u2013 investigated for sustained GH and IGF-1 signalling.<\/p>\n<p><strong>NOTA<\/strong>: Esto es solo para fines de referencia educativa y no constituye asesoramiento m\u00e9dico.<\/p>\n<p><strong>Descargo de responsabilidad<\/strong><br \/>\nEste producto se vende \u00fanicamente para fines de investigaci\u00f3n. No est\u00e1 destinado a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. El comprador asume toda la responsabilidad por su manipulaci\u00f3n y uso adecuados.<\/p>","protected":false},"excerpt":{"rendered":"<p>NAD+ (Nicotinamide Adenine Dinucleotide) 500 mg is a research-grade cellular coenzyme supplied in lyophilised form for laboratory use. As one of the most essential molecules in cellular metabolism, NAD+ is widely investigated for mitochondrial function, energy production, DNA repair and healthy aging research.<\/p>\n<p>||<\/p>\n<p>Purity \u226599% | EU Shipping from \u20ac5 | Free shipping upgrades available | Card payments accepted<\/p>","protected":false},"featured_media":1287,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[131],"product_tag":[361,329,383,325,384,382,364,380,381],"class_list":["post-1289","product","type-product","status-publish","has-post-thumbnail","product_cat-cellular-mitochondrial-research","product_tag-atp-production","product_tag-cellular-energy","product_tag-dna-repair","product_tag-healthy-aging","product_tag-longevity-research","product_tag-mitochondrial-function","product_tag-mitochondrial-research","product_tag-nad","product_tag-nicotinamide-adenine-dinucleotide","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/product\/1289","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/comments?post=1289"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/media\/1287"}],"wp:attachment":[{"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/media?parent=1289"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/product_brand?post=1289"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/product_cat?post=1289"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/life-peptide.com\/es\/wp-json\/wp\/v2\/product_tag?post=1289"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}