{"id":910,"date":"2026-04-27T16:55:29","date_gmt":"2026-04-27T13:55:29","guid":{"rendered":"https:\/\/life-peptide.com\/?post_type=product&#038;p=910"},"modified":"2026-07-21T11:11:23","modified_gmt":"2026-07-21T08:11:23","slug":"melanotan-2-10-mg","status":"publish","type":"product","link":"https:\/\/life-peptide.com\/fr\/product\/melanotan-2-10-mg\/","title":{"rendered":"Melanotan 2 (MT2) \/ 10 mg"},"content":{"rendered":"<p>Melanotan 2 (also known as Melanotan II or MT2) is one of the best-known research peptides for <strong>tanning and pigmentation studies<\/strong>. It is a synthetic <strong>analogue of \u03b1-melanocyte-stimulating hormone (\u03b1-MSH)<\/strong>, developed to investigate how melanocortin signalling regulates melanin production and the skin&#8217;s physiological response to ultraviolet (UV) exposure.<\/p>\n<p>Beyond pigmentation research, Melanotan 2 has played an important role in advancing our understanding of the melanocortin system. During early clinical investigations, researchers observed effects beyond skin pigmentation, leading to the later development of <a href=\"https:\/\/life-peptide.com\/fr\/product\/pt-141-10-mg\/\"><strong>PT-141 (Bremelanotide)<\/strong><\/a>, a more selective melanocortin peptide designed specifically for sexual function research.<\/p>\n<p>Today, Melanotan 2 remains one of the most extensively investigated peptides for pigmentation biology, melanocortin receptor signalling and neuroendocrine physiology.<\/p>\n<hr \/>\n<h4><strong>Why Melanotan 2 is widely investigated<\/strong><\/h4>\n<p>Published research has investigated Melanotan 2 in relation to:<\/p>\n<ul>\n<li>tanning research<\/li>\n<li>skin pigmentation<\/li>\n<li>melanin production<\/li>\n<li>melanogenesis<\/li>\n<li>UV-independent pigmentation<\/li>\n<li>melanocyte biology<\/li>\n<li>melanocortin receptor signalling<\/li>\n<li>appetite regulation<\/li>\n<li>neuroendocrine physiology<\/li>\n<\/ul>\n<p>Its broad receptor activity has made Melanotan 2 one of the foundational research peptides for understanding the melanocortin system.<\/p>\n<h4><strong>How Melanotan 2 promotes pigmentation<\/strong><\/h4>\n<p>Published research demonstrates that Melanotan 2 primarily <strong>activates the MC1 melanocortin receptor<\/strong>, which regulates melanin production within melanocytes.<\/p>\n<p>Research has explored its relationship with:<\/p>\n<p><strong>Melanin production<\/strong><\/p>\n<p>Activation of melanocytes and increased melanin synthesis, making Melanotan 2 one of the best-known peptides in pigmentation research.<\/p>\n<p><strong>UV response<\/strong><\/p>\n<p>Investigation of the relationship between melanocortin signalling, melanin production and the skin&#8217;s physiological response to ultraviolet exposure.<\/p>\n<p><strong>Pigmentation biology<\/strong><\/p>\n<p>Studies examining how melanocortin receptors regulate pigmentation across different skin types and experimental models.<\/p>\n<p>Because Melanotan 2 also activates other melanocortin receptors, researchers have investigated additional physiological pathways involving appetite regulation, energy balance and central nervous system signalling.<\/p>\n<h4><strong>Why Melanotan 2 became important beyond tanning research<\/strong><\/h4>\n<p>Although Melanotan 2 was originally developed for pigmentation research, investigators later discovered that melanocortin receptor activation also influenced central nervous system pathways involved in sexual behaviour.<\/p>\n<p>These findings ultimately led to the development of <a href=\"https:\/\/life-peptide.com\/fr\/product\/pt-141-10-mg\/\"><strong>PT-141 (Bremelanotide)<\/strong><\/a>, a more selective melanocortin peptide that focuses on sexual desire and arousal research rather than pigmentation.<\/p>\n<p>This makes Melanotan 2 one of the most influential peptides in the history of melanocortin research.<\/p>\n<hr \/>\n<h4><strong>Human and preclinical research<\/strong><\/h4>\n<p>Melanotan 2 has been investigated extensively in both laboratory and human studies.<\/p>\n<p>Published research includes:<\/p>\n<ul>\n<li>tanning physiology<\/li>\n<li>pigmentation biology<\/li>\n<li>melanogenesis<\/li>\n<li>UV response<\/li>\n<li>melanocortin receptor pharmacology<\/li>\n<li>appetite regulation<\/li>\n<li>neuroendocrine signalling<\/li>\n<\/ul>\n<p>Although newer melanocortin analogues have since been developed for more specific applications, Melanotan 2 remains one of the principal research compounds for studying the melanocortin receptor family.<\/p>\n<h4><strong>How Melanotan 2 differs from related peptides<\/strong><\/h4>\n<table style=\"height: 142px;\" width=\"730\">\n<thead>\n<tr>\n<th>Research objective<\/th>\n<th>Recommended peptide<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Tanning &amp; pigmentation research<\/strong><\/td>\n<td><strong>Melanotan 2<\/strong><\/td>\n<\/tr>\n<tr>\n<td><strong>Sexual desire &amp; arousal research<\/strong><\/td>\n<td><a href=\"https:\/\/life-peptide.com\/fr\/product\/pt-141-10-mg\/\"><strong>PT-141 (Bremelanotide)<\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td><strong>Reproductive hormone regulation<\/strong><\/td>\n<td><a href=\"https:\/\/life-peptide.com\/fr\/product\/kisspeptin-10-5-mg\/\"><strong>Kisspeptin-10<\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td><strong>Social bonding &amp; neuroendocrine behaviour<\/strong><\/td>\n<td><a href=\"https:\/\/life-peptide.com\/fr\/product\/oxytocin-5-mg\/\"><strong>Oxytocin<\/strong><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Although Melanotan 2 and PT-141 share a common developmental history, they are now investigated for different research objectives. Melanotan 2 primarily focuses on pigmentation and melanocortin biology, whereas PT-141 investigates central pathways involved in sexual desire and arousal.<\/p>\n<h4><strong>Published safety observations<\/strong><\/h4>\n<p>Published human studies have most commonly reported <strong>nausea, facial flushing, yawning and transient increases in skin pigmentation<\/strong>. Researchers have also observed increased pigmentation of freckles and existing moles, which has become an area of continued investigation. Current knowledge is based primarily on controlled clinical studies and experimental research, and long-term safety remains an active topic within the scientific literature.<\/p>\n<hr \/>\n<h4><strong>Product characteristics<\/strong><\/h4>\n<p>Application: laboratory and analytical research<br \/>\nUse restriction: not for human consumption; not for medical, veterinary or cosmetic use<br \/>\nProduced in GMP-compliant facilities under strict QC protocols.<br \/>\nEach batch carefully lab tested after production (you can find Certificate of Analysis under product pictures).<br \/>\nFreeze-dried (lyophilized) for maximum stability and extended shelf life.<br \/>\nSealed in sterile vials, ready for reconstitution.<br \/>\nPurity: \u2265 99% (HPLC)<br \/>\nAppearance: white lyophilized powder<br \/>\nMolecular formula: C<sub>50<\/sub>H<sub>69<\/sub>N<sub>15<\/sub>O<sub>9<\/sub><br \/>\nMolecular weight: 1024.2<br \/>\nCAS No: 121062-08-6<\/p>\n<p><strong>Storage<\/strong>: unopened lyophilized vials are best stored <strong>refrigerated at 2\u20138\u00b0C<\/strong>, which is the storage method confirmed by our manufacturing partner and suitable for up to 24 months. Refrigeration is preferred because it minimizes unnecessary freeze\u2013thaw cycles during routine handling. If substantially longer-term storage is required, unopened lyophilized vials may also be kept frozen. Once reconstituted, always store at 2\u20138\u00b0C and do not freeze.<\/p>\n<h4><strong>Reconstitution and handling<\/strong><\/h4>\n<p>Melanotan 2 is supplied as a lyophilised vial and should be handled using standard peptide reconstitution procedures appropriate to the research setting. Must be reconstituted with <a href=\"https:\/\/life-peptide.com\/fr\/product\/bac-10-ml\/\">bacteriostatic water<\/a> before use. To help preserve structural integrity, add the chosen solvent slowly against the inside wall of the vial rather than directly onto the peptide cake, and avoid vigorous shaking. Gentle swirling is generally sufficient once the peptide has fully dissolved. Standard laboratory practice also includes allowing refrigerated vials to reach room temperature before reconstitution to minimise condensation inside the vial.<\/p>\n<p>For other solvent selection, concentration planning and storage guidance, see the full <a href=\"https:\/\/life-peptide.com\/fr\/reconstitution-of-peptides\/\">Peptide Reconstitution Guide<\/a> et <a href=\"https:\/\/life-peptide.com\/fr\/calculator\/\">Reconstitution Calculator<\/a>.<\/p>\n<hr \/>\n<h4><strong>Selected research references<\/strong><\/h4>\n<ul>\n<li>Hadley ME. <em>Melanocortin Peptide Therapeutics: Historical Milestones, Clinical Studies and Commercialization, Peptides<\/em>, 2006<\/li>\n<\/ul>\n<p>A comprehensive review describing the development of Melanotan peptides, pigmentation research and the subsequent evolution of PT-141 from Melanotan 2.<\/p>\n<ul>\n<li>Dorr RT, et al. <em>Evaluation of Melanotan-II, a Superpotent Cyclic Melanotropic Peptide in a Pilot Phase I Clinical Study, Life Sciences<\/em>, 1996<\/li>\n<\/ul>\n<p>The first human clinical study evaluating Melanotan 2 and its effects on pigmentation.<\/p>\n<ul>\n<li>Habbema L, Halk AB, Neumann M, Bergman W. <em>Risks of Unregulated Use of Alpha-Melanocyte-Stimulating Hormone Analogues: A Review, International Journal of Dermatology<\/em>, 2017<\/li>\n<\/ul>\n<p>A review summarising the published evidence on Melanotan analogues, pigmentation effects and reported safety considerations.<\/p>\n<ul>\n<li>Wessells H, et al. <em>Melanocortin Receptor Agonists and Human Sexual Function, International Journal of Impotence Research,<\/em> 2000<\/li>\n<\/ul>\n<p>One of the early human studies showing central nervous system effects beyond pigmentation, contributing to the later development of PT-141.<\/p>\n<hr \/>\n<h4><strong>Questions fr\u00e9quemment pos\u00e9es<\/strong><\/h4>\n<p><strong>What is Melanotan 2?<\/strong><\/p>\n<p>Melanotan 2 is a synthetic analogue of \u03b1-melanocyte-stimulating hormone (\u03b1-MSH). It is one of the world&#8217;s most extensively investigated research peptides for tanning, pigmentation and melanocortin receptor biology.<\/p>\n<p><strong>How does Melanotan 2 promote pigmentation?<\/strong><\/p>\n<p>Melanotan 2 primarily activates the MC1 melanocortin receptor, which regulates melanin production within melanocytes. This has made it one of the leading research peptides for pigmentation and tanning studies.<\/p>\n<p><strong>How does Melanotan 2 differ from PT-141?<\/strong><\/p>\n<p>Although PT-141 was developed from Melanotan 2, the two peptides are investigated for different purposes. Melanotan 2 primarily focuses on pigmentation and melanocortin biology, while PT-141 is a more selective melanocortin peptide investigated mainly for sexual desire and arousal research.<\/p>\n<p><strong>Why is Melanotan 2 associated with appetite and sexual function research?<\/strong><\/p>\n<p>Melanotan 2 activates several melanocortin receptor subtypes in addition to MC1R, including receptors involved in appetite regulation and central nervous system signalling. Early studies unexpectedly observed effects on sexual function, which contributed to the later development of PT-141.<\/p>\n<p><strong>What research areas commonly investigate Melanotan 2?<\/strong><\/p>\n<p>Published research includes tanning physiology, skin pigmentation, melanogenesis, UV response, melanocortin receptor signalling, appetite regulation and neuroendocrine physiology.<\/p>\n<p><strong>How does Melanotan 2 differ from Melanotan 1 (Afamelanotide)?<\/strong><\/p>\n<p>Both peptides are derived from \u03b1-MSH, but Melanotan 2 activates multiple melanocortin receptor subtypes, whereas Afamelanotide is considerably more selective for MC1R. This broader receptor activity has made Melanotan 2 useful across a wider range of melanocortin research topics.<\/p>\n<p><strong>Is this product intended for human use?<\/strong><\/p>\n<p>No. Melanotan 2 supplied by LIFE Peptide is provided strictly for laboratory and analytical research. It is not intended for human consumption, diagnosis, treatment or prevention of disease. Any discussion of published studies summarises the current scientific literature relating to the Melanotan 2 molecule rather than the intended use of this product.<\/p>\n<hr \/>\n<h4><strong>Related research context<\/strong><\/h4>\n<p>Melanotan 2 belongs to the broader <a href=\"\/fr\/category\/sexual-function-and-melanocortin-peptides\/\">Melanocortin and neuroendocrine peptide research category<\/a>, focusing on pigmentation pathways and central melanocortin signaling mechanisms.<br \/>\nResearchers exploring related melanocortin pathway models may also examine:<br \/>\n\u2022 <a href=\"https:\/\/life-peptide.com\/fr\/product\/pt-141-10-mg\/\">PT-141 (Bremelanotide)<\/a> \u2014 selective melanocortin receptor signaling research<br \/>\n\u2022 <a href=\"\/fr\/category\/cognitive-research-peptides\/\">Cognitive &amp; neuroresearch peptides<\/a> \u2014 CNS peptide signaling models<\/p>\n<p><strong>NOTE<\/strong>: This is for educational reference only and does not constitute medical advice.<\/p>\n<p><strong>Disclaimer<\/strong><br \/>\nThis product is sold for research purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. Buyer assumes full responsibility for proper handling and use.<\/p>","protected":false},"excerpt":{"rendered":"<p>Melanotan 2 is a synthetic melanocortin peptide studied for its interaction with pigmentation pathways, melanocortin receptor signaling, and neuroendocrine research models.<\/p>\n<p>||<\/p>\n<p>Purity \u226599% | EU shipping from \u20ac5 | Free shipping upgrades available | Card payments accepted<\/p>","protected":false},"featured_media":1240,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[23],"product_tag":[224,135,219,137,227,136,220,134,226,133,225],"class_list":["post-910","product","type-product","status-publish","has-post-thumbnail","product_cat-sexual-function-and-melanocortin-peptides","product_tag-hypothalamic-signaling","product_tag-melanocortin","product_tag-melanocortin-peptide","product_tag-melanogenesis","product_tag-melanogenesis-research","product_tag-mt2","product_tag-neuroendocrine-signaling","product_tag-pigmentation","product_tag-pigmentation-pathways","product_tag-tanning","product_tag--msh-analogue","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/life-peptide.com\/fr\/wp-json\/wp\/v2\/product\/910","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/life-peptide.com\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/life-peptide.com\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/fr\/wp-json\/wp\/v2\/comments?post=910"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/fr\/wp-json\/wp\/v2\/media\/1240"}],"wp:attachment":[{"href":"https:\/\/life-peptide.com\/fr\/wp-json\/wp\/v2\/media?parent=910"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/life-peptide.com\/fr\/wp-json\/wp\/v2\/product_brand?post=910"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/life-peptide.com\/fr\/wp-json\/wp\/v2\/product_cat?post=910"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/life-peptide.com\/fr\/wp-json\/wp\/v2\/product_tag?post=910"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}