{"id":1289,"date":"2026-07-21T16:03:07","date_gmt":"2026-07-21T13:03:07","guid":{"rendered":"https:\/\/life-peptide.com\/?post_type=product&#038;p=1289"},"modified":"2026-07-21T16:03:09","modified_gmt":"2026-07-21T13:03:09","slug":"nad","status":"publish","type":"product","link":"https:\/\/life-peptide.com\/it\/product\/nad\/","title":{"rendered":"NAD+ \/ 500 mg"},"content":{"rendered":"<p>NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme found in every living cell.\u00a0Rather than acting as a signalling peptide or hormone, NAD+ functions as an essential electron carrier in hundreds of metabolic reactions, playing a central role in <strong>ATP production, mitochondrial function and cellular repair<\/strong>.<\/p>\n<p>Because NAD+ levels naturally decline with age and metabolic stress, it has become one of the most extensively investigated molecules in research on <strong>aging, energy metabolism and mitochondrial biology<\/strong>.<\/p>\n<hr \/>\n<h4><strong>Why NAD+ is widely investigated<\/strong><\/h4>\n<p>Published research has investigated NAD+ in relation to:<\/p>\n<ul>\n<li>cellular energy production<\/li>\n<li>mitochondrial function<\/li>\n<li>healthy aging<\/li>\n<li>DNA repair<\/li>\n<li>oxidative stress<\/li>\n<li>metabolic health<\/li>\n<li>cognitive function<\/li>\n<li>muscle physiology<\/li>\n<li>sirtuin biology<\/li>\n<\/ul>\n<p>Unlike mitochondrial peptides, NAD+ serves as a fundamental metabolic cofactor required for normal cellular function across virtually every tissue.<\/p>\n<h4><strong>How NAD+ works<\/strong><\/h4>\n<p><strong>Cellular energy production<\/strong><\/p>\n<p>NAD+ plays a central role in converting nutrients into usable cellular energy.\u00a0It transfers electrons during glycolysis, the citric acid cycle and oxidative phosphorylation, allowing mitochondria to generate ATP efficiently.<\/p>\n<p><strong>Mitochondrial function<\/strong><\/p>\n<p>Healthy mitochondria depend on adequate NAD+ availability to support normal energy metabolism.\u00a0Research has investigated how declining NAD+ levels influence mitochondrial performance during aging and metabolic stress.<\/p>\n<p><strong>DNA repair<\/strong><\/p>\n<p>NAD+ serves as an essential substrate for enzymes involved in DNA repair, including PARPs, which respond to DNA damage by helping maintain genomic stability.<\/p>\n<p><strong>Sirtuin activation<\/strong><\/p>\n<p>NAD+ is also required by sirtuins, a family of enzymes involved in cellular stress responses, metabolism and healthy aging.\u00a0This relationship has made NAD+ a central focus of longevity research.<\/p>\n<hr \/>\n<h4><strong>Why NAD+ is different from mitochondrial peptides<\/strong><\/h4>\n<p>Although frequently discussed together, NAD+, SS-31 and MOTS-c investigate different aspects of mitochondrial biology.<\/p>\n<p><strong>NAD+<\/strong> supplies an essential coenzyme required for cellular energy metabolism.<br \/>\n<a href=\"https:\/\/life-peptide.com\/it\/product\/ss-31\/\"><strong>SS-31<\/strong><\/a> investigates mitochondrial membrane integrity and ATP production.<br \/>\n<a href=\"https:\/\/life-peptide.com\/it\/product\/mots-c-10-mg\/\"><strong>MOTS-c<\/strong> <\/a>studies metabolic signalling and adaptive cellular responses.<\/p>\n<p>Together, these represent complementary areas of cellular energy research rather than competing mechanisms.<\/p>\n<h4><strong>Ricerca umana e preclinica<\/strong><\/h4>\n<p>NAD+ has been investigated extensively in both laboratory and clinical settings.<\/p>\n<p>Current research explores its role in <strong>aging, metabolic disorders, neurodegeneration, cardiovascular physiology and mitochondrial disease<\/strong>. Much of this work also focuses on strategies to increase intracellular NAD+ through precursors such as NMN and nicotinamide riboside, reflecting the importance of NAD+ homeostasis in human physiology.<\/p>\n<p>Although the biological importance of NAD+ is well established, many therapeutic applications remain under active investigation.<\/p>\n<h4><strong>Osservazioni di sicurezza pubblicate<\/strong><\/h4>\n<p>As a naturally occurring cellular coenzyme, NAD+ has been the subject of extensive biological research.<\/p>\n<p>Clinical investigations have generally reported favourable tolerability across a range of study designs, although research continues to evaluate optimal delivery methods, pharmacokinetics and potential applications in age-related disease.<\/p>\n<hr \/>\n<h3><strong>Caratteristiche del prodotto<\/strong><\/h3>\n<p>Applicazione: ricerca di laboratorio e analitica<br \/>\nUso limitato: non per il consumo umano; non per uso medico, veterinario o cosmetico<br \/>\nProdotto in stabilimenti conformi alle GMP secondo rigidi protocolli di controllo qualit\u00e0.<br \/>\nOgni lotto viene accuratamente testato in laboratorio dopo la produzione (puoi trovare il Certificato di Analisi sotto le immagini del prodotto).<br \/>\nLiofilizzato (liofilizzato) per la massima stabilit\u00e0 e una lunga durata di conservazione.<br \/>\nSigillato in fiale sterili, pronto per la ricostituzione.<br \/>\nPurity: \u2265 99.47% , HPLC tested<br \/>\nAspetto: polvere liofilizzata bianca<br \/>\nMolecular formula:\u00a0C<sub>21<\/sub>H<sub>29<\/sub>N<sub>7<\/sub>O<sub>14<\/sub>P<sub>2<\/sub><sup>2+<\/sup><br \/>\nMolecular weight: 665.4<\/p>\n<p><strong>Archiviazione<\/strong>flaconcini liofilizzati non aperti sono meglio conservati <strong>refrigerato a 2\u20138\u00b0C<\/strong>, che \u00e8 il metodo di conservazione confermato dal nostro partner di produzione e adatto fino a 24 mesi. Si preferisce la refrigerazione perch\u00e9 minimizza inutili cicli di congelamento-scongelamento durante la manipolazione di routine. Se \u00e8 necessaria una conservazione a termine sostanzialmente pi\u00f9 lungo, i flaconcini liofilizzati non aperti possono anche essere conservati congelati. Una volta ricostituita, conservare sempre a 2-8\u00b0C e non congelare.<\/p>\n<h4><strong>Ricostituzione e manipolazione<\/strong><\/h4>\n<p>NAD+ is supplied as a lyophilised vial and should be handled using standard peptide reconstitution procedures appropriate to the research setting. Must be reconstituted with <a href=\"https:\/\/life-peptide.com\/it\/product\/bac-10-ml\/\">acqua batteriostatica<\/a> prima dell'uso. Per aiutare a preservare l'integrit\u00e0 strutturale, aggiungere il solvente scelto lentamente contro la parete interna del flaconcino piuttosto che direttamente sulla polvere del peptide, ed evitare agitazioni vigorose. Il delicato movimento rotatorio \u00e8 generalmente sufficiente una volta che il peptide si \u00e8 completamente sciolto. La pratica standard di laboratorio include anche il far raggiungere ai flaconcini refrigerati la temperatura ambiente prima della ricostituzione per minimizzare la condensa all'interno del flaconcino.<\/p>\n<p>Per altre indicazioni sulla scelta del solvente, sulla pianificazione della concentrazione e sullo stoccaggio, consultare il pieno <a href=\"https:\/\/life-peptide.com\/it\/reconstitution-of-peptides\/\">Guida alla Ricostituzione dei Peptidi<\/a> e <a href=\"https:\/\/life-peptide.com\/it\/calculator\/\">Calcolatore di Ricostituzione<\/a>.<\/p>\n<hr \/>\n<h4><strong>Riferimenti di ricerca selezionati<\/strong><\/h4>\n<ul>\n<li>Covarrubias AJ, Perrone R, Grozio A, Verdin E. <em>NAD+ Metabolism and Its Roles in Cellular Processes During Ageing, Nature Reviews Molecular Cell Biology<\/em>, 2021.<\/li>\n<\/ul>\n<p>A comprehensive review of NAD+ biology, aging, metabolism and mitochondrial function.<\/p>\n<ul>\n<li>Yoshino J, Baur JA, Imai SI. <em>NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and Nicotinamide Riboside, Cell Metabolism<\/em>, 2018.<\/li>\n<\/ul>\n<p>A landmark review summarising NAD+ metabolism and strategies for restoring intracellular NAD+.<\/p>\n<ul>\n<li>Rajman L, Chwalek K, Sinclair DA.<em> Therapeutic Potential of NAD+ Boosting Molecules, Nature Reviews Drug Discovery<\/em>, 2018.<\/li>\n<\/ul>\n<p>A detailed overview of NAD+ biology and current therapeutic research.<\/p>\n<hr \/>\n<h4><strong>Domande Frequenti<\/strong><\/h4>\n<p><strong>What is NAD+?<\/strong><\/p>\n<p>NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme essential for cellular energy production, mitochondrial function and DNA repair.<\/p>\n<p><strong>Is NAD+ a peptide?<\/strong><\/p>\n<p>No. NAD+ is not a peptide. It is a naturally occurring coenzyme found in every living cell and plays a central role in energy metabolism.<\/p>\n<p><strong>Why is NAD+ important for mitochondria?<\/strong><\/p>\n<p>NAD+ acts as an electron carrier during cellular respiration, allowing mitochondria to produce ATP efficiently and maintain normal energy metabolism.<\/p>\n<p><strong>How is NAD+ different from MOTS-c?<\/strong><\/p>\n<p>Although both investigate mitochondrial biology, NAD+ functions as an essential metabolic coenzyme, whereas MOTS-c acts as a mitochondrial signalling peptide that regulates cellular metabolism.<\/p>\n<p><strong>How is NAD+ different from SS-31?<\/strong><\/p>\n<p>SS-31 investigates the structural integrity of mitochondria by targeting the inner mitochondrial membrane, while NAD+ serves as a fundamental coenzyme required for cellular energy production.<\/p>\n<p><strong>Questo prodotto \u00e8 destinato all'uso umano?<\/strong><\/p>\n<p>No. NAD+ supplied by LIFE Peptide is intended strictly for laboratory and analytical research. It is not intended for human consumption, diagnosis, treatment or prevention of disease.<\/p>\n<hr \/>\n<h4><strong>Contesto di ricerca correlato<\/strong><\/h4>\n<p>NAD+ is frequently discussed alongside other research compounds investigating cellular energy, mitochondrial biology and healthy aging, although each targets distinct biological mechanisms.<\/p>\n<p><a href=\"https:\/\/life-peptide.com\/it\/product\/ss-31\/\">SS-31<\/a> (Elamipretide) \u2013 investigated for mitochondrial repair and cellular energy production.<br \/>\n<a href=\"https:\/\/life-peptide.com\/it\/product\/mots-c-10-mg\/\">MOTS-c<\/a> \u2013 studied for metabolic signalling and exercise adaptation.<br \/>\n<a href=\"https:\/\/life-peptide.com\/it\/product\/epitalon-10-mg\/\">Epitalon<\/a> \u2013 investigated for telomere biology and healthy aging research.<br \/>\n<a href=\"https:\/\/life-peptide.com\/it\/product\/ghk-cu-50-mg\/\">GHK-Cu<\/a> \u2013 studied for tissue regeneration and cellular repair.<br \/>\n<a href=\"https:\/\/life-peptide.com\/it\/product\/cjc-1295-with-dac\/\">CJC-1295 con DAC<\/a> \u2013 investigated for sustained GH and IGF-1 signalling.<\/p>\n<p><strong>NOTA<\/strong>: Questo \u00e8 solo a scopo didattico e non costituisce parere medico.<\/p>\n<p><strong>Disclaimer<\/strong><br \/>\nQuesto prodotto \u00e8 venduto esclusivamente a scopo di ricerca. Non \u00e8 destinato a diagnosticare, trattare, curare o prevenire alcuna malattia. L'acquirente si assume la piena responsabilit\u00e0 per la corretta manipolazione e utilizzo.<\/p>","protected":false},"excerpt":{"rendered":"<p>NAD+ (Nicotinamide Adenine Dinucleotide) 500 mg is a research-grade cellular coenzyme supplied in lyophilised form for laboratory use. As one of the most essential molecules in cellular metabolism, NAD+ is widely investigated for mitochondrial function, energy production, DNA repair and healthy aging research.<\/p>\n<p>||<\/p>\n<p>Purity \u226599% | EU Shipping from \u20ac5 | Free shipping upgrades available | Card payments accepted<\/p>","protected":false},"featured_media":1287,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[131],"product_tag":[361,329,383,325,384,382,364,380,381],"class_list":["post-1289","product","type-product","status-publish","has-post-thumbnail","product_cat-cellular-mitochondrial-research","product_tag-atp-production","product_tag-cellular-energy","product_tag-dna-repair","product_tag-healthy-aging","product_tag-longevity-research","product_tag-mitochondrial-function","product_tag-mitochondrial-research","product_tag-nad","product_tag-nicotinamide-adenine-dinucleotide","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/product\/1289","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/comments?post=1289"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/media\/1287"}],"wp:attachment":[{"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/media?parent=1289"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/product_brand?post=1289"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/product_cat?post=1289"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/product_tag?post=1289"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}