{"id":874,"date":"2026-04-23T15:39:24","date_gmt":"2026-04-23T12:39:24","guid":{"rendered":"https:\/\/life-peptide.com\/?post_type=product&#038;p=874"},"modified":"2026-07-21T11:15:14","modified_gmt":"2026-07-21T08:15:14","slug":"thymosin-%ce%b24-1-43-full-sequence-5-mg","status":"publish","type":"product","link":"https:\/\/life-peptide.com\/it\/product\/thymosin-%ce%b24-1-43-full-sequence-5-mg\/","title":{"rendered":"TB-500 (Sequenza completa della timosina \u03b24) \/ 5 mg"},"content":{"rendered":"<p>TB-500 is the name most commonly used within the research community for peptides derived from <strong>Thymosin \u03b24<\/strong> biology. Depending on the supplier and historical context, the term may refer to different peptide preparations. This product contains the <strong>complete Thymosin \u03b24 (1\u201343) sequence<\/strong>, allowing researchers to investigate the full endogenous peptide rather than a shortened derivative.<\/p>\n<p>Thymosin \u03b24 is a <strong>naturally occurring 43-amino-acid peptide<\/strong> present in numerous human tissues. It plays important roles in <strong>actin regulation, cell migration, angiogenesis and tissue remodelling<\/strong>, making it one of the best-studied endogenous peptides in regenerative biology. Because TB-500 has become the dominant search term within the peptide community, the two names are frequently associated, even though they are not always scientifically identical.<\/p>\n<hr \/>\n<h4><strong>Why TB-500 matters in regenerative research<\/strong><\/h4>\n<p>TB-500 has become one of the most widely recognised regenerative peptides because published research on Thymosin \u03b24 biology has demonstrated involvement in multiple repair-related processes rather than a single signalling pathway.<\/p>\n<p>Research has investigated TB-500 \/ Thymosin \u03b24 in relation to:<\/p>\n<ul>\n<li><strong>tissue repair<\/strong><\/li>\n<li><strong>wound healing<\/strong><\/li>\n<li><strong>angiogenesi<\/strong><\/li>\n<li><strong>cell migration<\/strong><\/li>\n<li><strong>actin dynamics<\/strong><\/li>\n<li><strong>tendon and ligament biology<\/strong><\/li>\n<li><strong>skeletal muscle repair<\/strong><\/li>\n<li><strong>cardiac tissue research<\/strong><\/li>\n<li><strong>corneal regeneration<\/strong><\/li>\n<li><strong>segnalazione infiammatoria<\/strong><\/li>\n<\/ul>\n<p>Unlike peptides that primarily target a single receptor, Thymosin \u03b24 influences several interconnected biological processes involved in tissue maintenance and repair, making it relevant across multiple fields of regenerative research.<\/p>\n<h4><strong>How TB-500 works<\/strong><\/h4>\n<p>The biological activity associated with TB-500 originates from Thymosin \u03b24, an endogenous peptide that binds G-actin, helping regulate cytoskeletal organisation and cellular movement.<\/p>\n<p>Published research has linked Thymosin \u03b24 to:<\/p>\n<ul>\n<li>regulation of actin dynamics<\/li>\n<li>cell migration<\/li>\n<li>angiogenesi<\/li>\n<li>extracellular matrix remodelling<\/li>\n<li>inflammatory responses<\/li>\n<li>tissue regeneration<\/li>\n<\/ul>\n<p>Because successful tissue repair depends on coordinated cell migration and structural remodelling, Thymosin \u03b24 has become an important experimental model in regenerative medicine and wound-healing research.<\/p>\n<hr \/>\n<h4><strong>Ricerca umana e preclinica<\/strong><\/h4>\n<p>Published studies investigating Thymosin \u03b24 have explored its biological activity across numerous laboratory models together with several early-stage human clinical programmes.<\/p>\n<p>Research has examined its role in:<\/p>\n<ul>\n<li>dermal wound healing<\/li>\n<li>corneal repair<\/li>\n<li>myocardial injury<\/li>\n<li>pressure ulcers<\/li>\n<li>venous ulcers<\/li>\n<li>musculoskeletal regeneration<\/li>\n<\/ul>\n<p>While early clinical studies reported encouraging biological activity and favourable tolerability, the current evidence base remains substantially smaller than that available for approved therapeutic agents. Consequently, TB-500 \/ Thymosin \u03b24 continues to be investigated primarily as a research peptide rather than an established medicine.<\/p>\n<hr \/>\n<h4><strong>Understanding TB-500 and full-sequence Thymosin \u03b24<\/strong><\/h4>\n<p>Although TB-500 is by far the most widely recognised name within the peptide community, the scientific literature primarily investigates Thymosin \u03b24, the naturally occurring endogenous peptide.<\/p>\n<p>This product contains the<strong> complete Thymosin \u03b24 (1\u201343) sequence<\/strong>, consisting of all 43 amino acids found in the native human peptide.<\/p>\n<p>This distinction matters because:<\/p>\n<ul>\n<li>many published mechanistic and clinical studies investigated the full-length peptide<\/li>\n<li>the term TB-500 has been used inconsistently by different suppliers over the years<\/li>\n<li>not every product marketed as TB-500 necessarily represents the complete endogenous sequence<\/li>\n<\/ul>\n<p>For researchers seeking to align experimental work with the published Thymosin \u03b24 literature, using the full-sequence peptide provides the closest match to the molecule investigated in most biological studies while still matching the terminology most researchers search for online.<\/p>\n<h4><strong>How TB-500 differs from BPC-157 and GHK-Cu<\/strong><\/h4>\n<p>Although TB-500, BPC-157 and GHK-Cu are frequently grouped together as regenerative peptides, they represent distinct biological approaches.<\/p>\n<p><strong>TB-500 \/ Thymosin \u03b24<\/strong> is primarily associated with cell migration, actin dynamics and tissue remodelling, making it particularly relevant for studies of coordinated tissue repair.<\/p>\n<p><a href=\"https:\/\/life-peptide.com\/it\/product\/bpc-157-5-mg\/\"><strong>BPC-157<\/strong><\/a> is more commonly investigated in tendon, ligament, muscle and gastrointestinal injury models, with particular interest in angiogenesis and cytoprotective signalling.<\/p>\n<p><a href=\"https:\/\/life-peptide.com\/it\/product\/ghk-cu-50-mg\/\"><strong>GHK-Cu<\/strong><\/a> is a naturally occurring copper peptide studied for extracellular matrix biology, collagen turnover, skin physiology and broad gene-regulatory effects.<\/p>\n<p>Rather than competing with one another, these peptides are often viewed as <strong>complementary research tools<\/strong> targeting different aspects of regenerative biology.<\/p>\n<hr \/>\n<h4><strong>Osservazioni di sicurezza pubblicate<\/strong><\/h4>\n<p>Early human clinical studies investigating full-sequence Thymosin \u03b24 have generally reported <strong>favourable tolerability<\/strong> under controlled research conditions.<\/p>\n<p>Phase I clinical programmes evaluating intravenous administration found no dose-limiting toxicity within the investigated dose ranges, while subsequent studies continued to evaluate safety in cardiovascular, ophthalmic and tissue-repair settings.<\/p>\n<p>Because published human data remain relatively limited and involve different formulations and research objectives, current safety findings should be interpreted within the context of each individual study.<\/p>\n<hr \/>\n<h4><strong>Caratteristiche del prodotto<\/strong><\/h4>\n<p>Applicazione: ricerca di laboratorio e analitica<br \/>\nUso limitato: non per il consumo umano; non per uso medico, veterinario o cosmetico<br \/>\nProdotto in stabilimenti conformi alle GMP secondo rigidi protocolli di controllo qualit\u00e0.<br \/>\nOgni lotto viene accuratamente testato in laboratorio dopo la produzione (puoi trovare il Certificato di Analisi sotto le immagini del prodotto).<br \/>\nLiofilizzato (liofilizzato) per la massima stabilit\u00e0 e una lunga durata di conservazione.<br \/>\nSigillato in fiale sterili, pronto per la ricostituzione.<br \/>\nPurity: \u2265 99% (HPLC)<br \/>\nAspetto: polvere liofilizzata bianca<br \/>\nFormula molecolare: C<sub>212<\/sub>H<sub>350<\/sub>N<sub>56<\/sub> O<sub>78<\/sub>S<br \/>\nMolecular weight: 4963.49<br \/>\nCAS No: 77591-33-4<br \/>\nSequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH<br \/>\n<strong>Archiviazione<\/strong>flaconcini liofilizzati non aperti sono meglio conservati <strong>refrigerato a 2\u20138\u00b0C<\/strong>, che \u00e8 il metodo di conservazione confermato dal nostro partner di produzione e adatto fino a 24 mesi. Si preferisce la refrigerazione perch\u00e9 minimizza inutili cicli di congelamento-scongelamento durante la manipolazione di routine. Se \u00e8 necessaria una conservazione a termine sostanzialmente pi\u00f9 lungo, i flaconcini liofilizzati non aperti possono anche essere conservati congelati. Una volta ricostituita, conservare sempre a 2-8\u00b0C e non congelare.<\/p>\n<h4><strong>Ricostituzione e manipolazione<\/strong><\/h4>\n<p>TB-500 is supplied as a lyophilised peptide and should be reconstituted using appropriate laboratory procedures suitable for peptide research. To help preserve structural integrity, add the chosen solvent slowly against the inside wall of the vial rather than directly onto the peptide cake, and avoid vigorous shaking. Gentle swirling is generally sufficient once the peptide has fully dissolved. Standard laboratory practice also includes allowing refrigerated vials to reach room temperature before reconstitution to minimise condensation inside the vial.<\/p>\n<p>Most often TB-500 is reconstituted with <a href=\"https:\/\/life-peptide.com\/it\/product\/bac-10-ml\/\">acqua batteriostatica<\/a> before use. For sterile filtration of peptide solutions it is advised to use a <a href=\"https:\/\/life-peptide.com\/it\/product\/022-m-pes-syringe-filters\/\">0.22 \u00b5m PES syringe filter<\/a>. For other solvent selection, concentration planning and storage guidance, see the full <a href=\"https:\/\/life-peptide.com\/it\/reconstitution-of-peptides\/\">Guida alla Ricostituzione dei Peptidi<\/a> e <a href=\"https:\/\/life-peptide.com\/it\/calculator\/\">Calcolatore di Ricostituzione<\/a>.. These resources explain how different reconstitution volumes affect working concentration without recommending research protocols.<\/p>\n<hr \/>\n<h4><strong>Studi chiave pubblicati<\/strong><\/h4>\n<ul>\n<li>Goldstein AL, Kleinman HK. <em>Thymosin \u03b24: Structure, Function and Biological Properties Supporting Current and Future Clinical Applications. Annals of the New York Academy of Sciences<\/em>, 2010.<\/li>\n<\/ul>\n<p>A landmark review describing the biological functions of full-sequence Thymosin \u03b24, including tissue repair, angiogenesis, inflammation and regenerative medicine.<\/p>\n<ul>\n<li>Ruff D, Crockford D, Girardi G, et al. <em>A Randomized, Placebo-Controlled, Single and Multiple Dose Study of Intravenous Thymosin \u03b24 in Healthy Volunteers. Annals of the New York Academy of Sciences<\/em>, 2010.<\/li>\n<\/ul>\n<p>The first Phase I human study evaluating the safety, tolerability and pharmacological profile of full-sequence Thymosin \u03b24.<\/p>\n<ul>\n<li>Xing Y, Zhang Y, Li Y, et al. <em>Progress on the Function and Application of Thymosin \u03b24. International Journal of Molecular Sciences<\/em>, 2021.<\/li>\n<\/ul>\n<p>A comprehensive review covering actin regulation, angiogenesis, wound healing, inflammation and current directions in regenerative research.<\/p>\n<ul>\n<li>Wang X, Liu L, Qi L, et al. <em>A First-in-Human, Randomized, Double-Blind, Single- and Multiple-Dose Phase I Study of Recombinant Human Thymosin \u03b24 in Healthy Chinese Volunteers. Journal of Cellular and Molecular Medicine<\/em>, 2021.<\/li>\n<\/ul>\n<p>A modern Phase I study describing safety, pharmacokinetics and tolerability of recombinant full-sequence Thymosin \u03b24 in healthy volunteers.<\/p>\n<hr \/>\n<h4><strong>Domande frequenti<\/strong><\/h4>\n<p><strong>What is TB-500?<\/strong><\/p>\n<p>TB-500 is the name most commonly used within the peptide research community for peptides associated with Thymosin \u03b24 biology. This product contains the complete Thymosin \u03b24 (1\u201343) sequence, allowing researchers to investigate the full endogenous peptide.<\/p>\n<p><strong>Is TB-500 the same as Thymosin \u03b24?<\/strong><\/p>\n<p>The names are often used interchangeably, but they are not always scientifically equivalent. Thymosin \u03b24 is the naturally occurring 43-amino-acid peptide found in human tissues, while the term TB-500 has historically been applied to different research peptide preparations. This product contains the full-length Thymosin \u03b24 sequence.<\/p>\n<p><strong>Why does the full sequence matter?<\/strong><\/p>\n<p>Many published mechanistic and clinical studies have investigated the complete endogenous Thymosin \u03b24 molecule. Using the full 43-amino-acid sequence allows researchers to work with a peptide that most closely reflects the molecule described throughout the scientific literature.<\/p>\n<p><strong>What research areas commonly investigate TB-500?<\/strong><\/p>\n<p>Published studies have investigated Thymosin \u03b24 biology in tissue repair, wound healing, angiogenesis, cell migration, tendon and ligament research, cardiac repair, corneal regeneration and regenerative medicine.<\/p>\n<p><strong>How does TB-500 differ from BPC-157<\/strong>?<\/p>\n<p>Although both peptides are widely studied in regenerative research, TB-500 is primarily associated with actin regulation, cell migration and tissue remodelling, whereas BPC-157 is more commonly investigated in soft-tissue injury models, angiogenesis and cytoprotective signalling.<\/p>\n<p><strong>Questo prodotto \u00e8 destinato all'uso umano?<\/strong><\/p>\n<p>No. TB-500 (Full Sequence Thymosin \u03b24) supplied by LIFE Peptide is provided strictly for laboratory and analytical research. It is not intended for human consumption, diagnosis, treatment or prevention of disease. Any discussion of published studies summarises the scientific literature relating to the peptide rather than the intended use of this product.<\/p>\n<hr \/>\n<h4><strong>Contesto di ricerca correlato<\/strong><\/h4>\n<p>Thymosin \u03b24 belongs to the healing &amp; recovery peptide research cluster, focused on tissue signaling, cellular repair mechanisms, and inflammatory pathway modulation.<br \/>\nResearchers studying these pathways may also examine:<\/p>\n<p><a href=\"https:\/\/life-peptide.com\/it\/product\/bpc-157-5-mg\/\">BPC-157<\/a> \u2013 tissue signaling peptide<br \/>\n<a href=\"https:\/\/life-peptide.com\/it\/product\/ghk-cu-50-mg\/\">GHK-Cu<\/a> \u2013 copper peptide complex<br \/>\n<a href=\"https:\/\/life-peptide.com\/it\/product\/kpv-5-mg\/\">KPV<\/a> \u2013 anti-inflammatory peptide fragment<br \/>\n<a href=\"https:\/\/life-peptide.com\/it\/product\/ara-290\/\">ARA-290<\/a> \u2013 erythropoietin-derived peptide<br \/>\n<a href=\"https:\/\/life-peptide.com\/it\/product\/ss-31\/\">SS-31<\/a> \u2013 indagata per la funzione mitocondriale e la produzione di energia cellulare.<\/p>\n<p>For broader context, see the <a href=\"\/it\/healing-recovery-research-guide\/\">Healing &amp; recovery research guide<\/a>.<br \/>\nSfoglia tutti i composti in\u00a0<a href=\"https:\/\/life-peptide.com\/it\/categoria\/peptidi-curativi\/\">Healing &amp; recovery research category<\/a>.<\/p>\n<p><strong>NOTA<\/strong>: Questo \u00e8 solo a scopo didattico e non costituisce parere medico.<br \/>\nThis product is supplied as full-sequence Thymosin \u03b24 (1\u201343)<br \/>\nNot labeled or marketed as \u201cTB-500\u201d to avoid ambiguity<br \/>\nIntended strictly for controlled laboratory environments<\/p>\n<p><strong>Disclaimer<\/strong><br \/>\nQuesto prodotto \u00e8 venduto esclusivamente a scopo di ricerca. Non \u00e8 destinato a diagnosticare, trattare, curare o prevenire alcuna malattia. L'acquirente si assume la piena responsabilit\u00e0 per la corretta manipolazione e utilizzo.<\/p>","protected":false},"excerpt":{"rendered":"<p>TB-500 (Thymosin \u03b24 Full Sequence) 5 mg is a research-grade regenerative peptide supplied in lyophilised form for laboratory use. Based on the complete 43-amino-acid Thymosin \u03b24 sequence, it has become an important research tool in studies of tissue repair, cell migration, angiogenesis and regenerative biology.<\/p>\n<p>||<\/p>\n<p>Purity \u226599% | EU <strong>Shipping from \u20ac5 | Free shipping upgrades available | Card payments accepted<\/strong><\/p>\n<p>&nbsp;<\/p>","protected":false},"featured_media":876,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[20],"product_tag":[181,300,184,182,297,185,192,296,294,295,282,187,298,195,183,299],"class_list":["post-874","product","type-product","status-publish","has-post-thumbnail","product_cat-healing-peptides","product_tag-actin-binding-peptide","product_tag-angiogenesis","product_tag-angiogenesis-research","product_tag-cell-migration-peptide","product_tag-connective-tissue","product_tag-cytoskeletal-regulation","product_tag-healing-peptide","product_tag-joint-research","product_tag-ligament-research","product_tag-muscle-recovery","product_tag-recovery-peptide","product_tag-regenerative-research-peptides","product_tag-skin-research","product_tag-tendon-research","product_tag-tissue-signaling-peptide","product_tag-wound-healing","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/product\/874","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/comments?post=874"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/media\/876"}],"wp:attachment":[{"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/media?parent=874"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/product_brand?post=874"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/product_cat?post=874"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/life-peptide.com\/it\/wp-json\/wp\/v2\/product_tag?post=874"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}