Melanocortin peptide for pigmentation and neuroendocrine signaling research

Melanotan 2 (MT-2) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH), investigated for its interaction with melanocortin receptor pathways involved in pigmentation signaling, neuroendocrine response mechanisms, and central nervous system peptide activity.
Researchers commonly study Melanotan 2 for its activity at melanocortin receptors, particularly MC1R and MC4R, which are associated with melanogenesis pathways, behavioral signaling, and hypothalamic neuropeptide regulation. Due to its broad receptor interaction profile, MT-2 has become one of the most widely investigated melanocortin peptides in experimental research models.
Unlike more selective melanocortin compounds such as PT-141, Melanotan 2 is researched across both pigmentation-related and neuroendocrine signaling pathways, making it a broader melanocortin research model within peptide signaling studies.

Research applications (investigational)

Melanotan 2 has been investigated in preclinical and experimental settings for its involvement in:

Melanocortin receptor signaling (MC1R/MC4R)
Pigmentation and melanogenesis pathway research
Neuroendocrine and hypothalamic signaling interaction
Behavioral and motivational response models
α-MSH analogue pathway investigation
Central nervous system peptide signaling dynamics
Comparative melanocortin pathway analysis

These areas reflect ongoing scientific investigation into melanocortin-mediated signaling mechanisms rather than established applications.

Product characteristics

Purity: ≥ 99% (HPLC)
Appearance: white lyophilized powder
Molecular formula: C₅₀H₆₉N₁₅O₉
Molecular weight: 1024.2
CAS No: 121062-08-6
Storage: store lyophilized powder at -20°C, protect from light and moisture. Reconstituted solution should be kept at 2–8°C and used within a short period.

Why choose our Melanotan 2

High-purity peptide verified by HPLC
Produced under strict GMP-compliant manufacturing and QC standards
Batch-tested with Certificate of Analysis available on the product page
Lyophilized for stability and consistent storage conditions
Supplied in sterile sealed vials prepared for laboratory reconstitution workflows
Reconstitution: Typically reconstituted with bacteriostatic water using gentle swirling to maintain peptide stability.

Selected research references

Hadley ME et al. Melanocortin peptides and melanogenesis signaling pathways. Pigment Cell Research, 1998.
Hruby VJ et al. Melanocortin receptor agonists and peptide signaling research. Current Medicinal Chemistry, 2001.
Wessells H et al. Melanocortin receptor agonists in neuroendocrine research models. Journal of Urology, 2000.
Abdel-Malek ZA et al. Melanocortin signaling and pigmentation biology. Annals of the New York Academy of Sciences, 2003.

Related research context

Melanotan 2 belongs to the broader Melanocortin and neuroendocrine peptide research category, focusing on pigmentation pathways and central melanocortin signaling mechanisms.
Researchers exploring related melanocortin pathway models may also examine:
• PT-141 (Bremelanotide) — selective melanocortin receptor signaling research
• Cognitive & neuroresearch peptides — CNS peptide signaling models

NOTE: This is for educational reference only and does not constitute medical advice.

Disclaimer
This product is sold for research purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. Buyer assumes full responsibility for proper handling and use.

pigmentation

Melanotan 2 / 10 mg