BPC-157 / 5 mg

Περιγραφή

BPC-157 (Body Protection Compound-157) is a synthetic 15-amino-acid peptide derived from a protective protein naturally present in human gastric juice. It is commonly described in the scientific literature as a stable gastric pentadecapeptide, reflecting both its biological origin and its unusual stability under experimental conditions.

Unlike many regenerative peptides that originate from endocrine or immune signalling, BPC-157 emerged from gastrointestinal research before becoming widely investigated across musculoskeletal, vascular and connective tissue biology.

Today it is one of the most extensively studied experimental peptides in regenerative research, particularly in models involving soft-tissue repair, angiogenesis and cytoprotective signalling.

Why BPC-157 matters in regenerative research

One of the reasons BPC-157 has attracted so much scientific interest is the breadth of tissues and biological systems investigated in experimental research. Published studies have explored BPC-157 in relation to:

• tendon repair
• ligament healing
• skeletal muscle biology
• joint and connective tissue research
• angiogenesis
• gastrointestinal protection
• inflammatory signalling
• nitric oxide pathways
• peripheral nerve research
• soft-tissue regeneration

Because tendon, ligament and muscle injuries are common in physically active populations, BPC-157 has also become one of the most recognised peptides in sports medicine and musculoskeletal recovery research, although the majority of published evidence remains preclinical. Although these findings have generated considerable interest, most of the available evidence comes from laboratory and animal studies rather than large human clinical trials.

How BPC-157 works

Unlike peptides that primarily activate a single receptor, BPC-157 appears to influence several interconnected biological pathways involved in tissue repair. Published experimental research has investigated its relationship with:

• Angiogenesis

Formation of new blood vessels and vascular repair signalling.

• Nitric oxide pathways

Modulation of nitric oxide systems involved in vascular function and tissue repair.

• Tendon and connective tissue biology

Studies have explored fibroblast activity, collagen organisation and tendon healing responses following injury.

• Cytoprotection

Research has also examined protective effects in gastrointestinal tissues together with broader cellular stress responses.

Rather than representing one isolated mechanism, BPC-157 is generally investigated as a peptide influencing multiple aspects of regenerative biology simultaneously.

What makes BPC-157 different from other regenerative peptides?

Although BPC-157, TB-500 and GHK-Cu are often grouped together within regenerative research, they represent different biological approaches.

ΒΡC-157

• Stable gastric pentadecapeptide
• Soft-tissue and musculoskeletal research
• Tendon and ligament biology
• Angiogenesis
• Nitric oxide signalling
• Cytoprotection

TB-500

• Thymosin β4 biology
• Cell migration
• Actin dynamics
• Tissue remodelling

GHK-Cu

• Endogenous copper peptide
• Collagen biology
• Extracellular matrix regulation
• Skin and connective tissue physiology

Rather than competing directly, these peptides are frequently discussed together because they target different aspects of tissue repair and regenerative biology.

Δημοσιευθείσες παρατηρήσεις ασφαλείας

Published experimental studies have generally reported favourable safety findings for BPC-157 within the investigated models.

However, compared with its extensive laboratory literature, human clinical evidence remains limited. Current understanding of BPC-157 therefore relies predominantly on preclinical research, and findings should be interpreted within that context.

Συχνές Ερωτήσεις

What is BPC-157?

BPC-157 (Body Protection Compound-157) is a synthetic 15-amino-acid peptide derived from a protective protein naturally present in human gastric juice. It is widely recognised in regenerative research for studies involving tissue repair, tendon and ligament biology, angiogenesis and gastrointestinal protection. Because of its broad experimental research profile, BPC-157 has become one of the best-known peptides in musculoskeletal and regenerative biology.

Why is BPC-157 called a stable gastric pentadecapeptide?

The term “stable gastric pentadecapeptide” reflects both the origin and the structure of BPC-157. It is derived from a naturally occurring protective gastric protein, contains 15 amino acids (hence pentadecapeptide), and demonstrates unusual stability under experimental conditions compared with many other peptides. These characteristics originally made it an important subject in gastrointestinal research before its investigation expanded into connective tissue and regenerative biology.

Why is BPC-157 widely investigated in tendon and ligament research?

Published experimental studies have investigated BPC-157 in numerous models involving tendons, ligaments, muscles and other connective tissues. Researchers have explored its relationship with angiogenesis, fibroblast activity, collagen organisation and tissue repair processes, making it one of the most frequently discussed peptides in musculoskeletal and sports medicine research. Although these findings have generated considerable interest, the majority of available evidence comes from laboratory and animal studies rather than large human clinical trials.

How does BPC-157 differ from TB-500?

Although both peptides are frequently associated with regenerative research, they have different biological backgrounds. BPC-157 originated from gastrointestinal research and is commonly investigated in tendon, ligament, muscle, vascular and cytoprotective models. TB-500 is associated with Thymosin β4 biology and is more closely linked to cell migration, actin dynamics and tissue remodelling. Rather than being direct alternatives, they are often viewed as complementary research tools.

How does BPC-157 differ from GHK-Cu?

GHK-Cu is a naturally occurring copper-binding tripeptide primarily investigated for extracellular matrix regulation, collagen biology, skin physiology and connective tissue remodelling. BPC-157, by comparison, is more commonly studied in soft-tissue repair, musculoskeletal research, gastrointestinal protection and angiogenesis. While both appear in regenerative research, they target different biological pathways and research questions.

What research areas commonly investigate BPC-157?

Published research has investigated BPC-157 across a broad range of experimental models, including tendon and ligament biology, skeletal muscle, gastrointestinal protection, angiogenesis, peripheral nerve research, nitric oxide signalling, inflammatory pathways and connective tissue repair. This broad research profile is one of the reasons BPC-157 remains one of the most widely recognised regenerative peptides.

Αυτό το προϊόν προορίζεται για ανθρώπινη χρήση;

No. BPC-157 supplied by LIFE Peptide is provided strictly for laboratory and analytical research. It is not intended for human consumption, diagnosis, treatment or prevention of disease. Any discussion of published studies on this page is included to summarise the current scientific literature relating to the BPC-157 molecule and should not be interpreted as instructions or recommendations for use.

Χαρακτηριστικά προϊόντος

Εφαρμογή: εργαστηριακή και αναλυτική έρευνα
Χρήση περιορισμού: όχι για ανθρώπινη κατανάλωση· όχι για ιατρική, κτηνιατρική ή καλλυντική χρήση
Παράγεται σε εγκαταστάσεις που συμμορφώνονται με τις ΟGMP υπό αυστηρά πρωτόκολλα ΠΚ.
Κάθε παρτίδα ελέγχεται προσεκτικά στο εργαστήριο μετά την παραγωγή (μπορείτε να βρείτε το Πιστοποιητικό Ανάλυσης κάτω από τις εικόνες του προϊόντος).
Κατάψυξη-αποξήρανση (λυσόφιλη) για μέγιστη σταθερότητα και παρατεταμένη διάρκεια ζωής.
Σφραγισμένα σε αποστειρωμένες φιάλες, έτοιμα για ανασύσταση.
Purity: ≥98.8% (HPLC-tested)
Appearance: Lyophilized white/off-white powder
Μοριακός τύπος: C₆₂H₉₈N₁₆O₂₂
Molecular weight: 1419.54 g/mol
Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Αποθήκευση: τα αφυδατωμένα σε ξηρή ψύξη, σφραγισμένα φιαλίδια φυλάσσονται καλύτερα συντήρηση στους 2–8°C, η οποία είναι η μέθοδος αποθήκευσης που επιβεβαιώθηκε από τον συνεργάτη παραγωγής μας και είναι κατάλληλη για έως και 24 μήνες. Η ψύξη προτιμάται επειδή ελαχιστοποιεί τους περιττούς κύκλους ψύξης-απόψυξης κατά τον συνήθη χειρισμό. Εάν απαιτείται σημαντικά μακροχρόνια αποθήκευση, τα σφραγισμένα λυοφιλοποιημένα φιαλίδια μπορούν επίσης να διατηρηθούν κατεψυγμένα. Μόλις ανασυσταθεί, αποθηκεύετε πάντα σε 2–8°C και μην καταψύχετε.

Ανα

BPC-157 is supplied as a lyophilised vial and should be handled using standard peptide reconstitution procedures appropriate to the research setting. Must be reconstituted with Βακτηριοστατικό νερό πριν τη χρήση. Για να διατηρηθεί η δομική ακεραιότητα, προσθέστε το επιλεγμένο διαλύτη αργά στο εσωτερικό τοίχωμα του φιαλιδίου αντί απευθείας στη μάζα του πεπτιδίου, και αποφύγετε το έντονο ανακίνημα. Η απαλή περιστροφή είναι γενικά επαρκής μόλις το πεπτίδιο διαλυθεί πλήρως. Η τυπική εργαστηριακή πρακτική περιλαμβάνει επίσης την αναμονή των ψυχόμενων φιαλιδίων να φτάσουν σε θερμοκρασία δωματίου πριν από την ανασύσταση για να ελαχιστοποιηθεί η συμπύκνωση στο εσωτερικό του φιαλιδίου.

Για την επιλογή άλλων διαλυτών, σχεδιασμό συγκεντρώσεων και οδηγίες αποθήκευσης, δείτε το πλήρες Οδηγός Ανασύστασης Πεπτιδίων και Υπολογιστής Απεικόνισης.

Βασικές δημοσιευμένες μελέτες

• Sikiric P, Seiwerth S, Rucman R, et al. Stable Gastric Pentadecapeptide BPC 157: Novel Therapy in Gastrointestinal Tract. Current Pharmaceutical Design, 2011.

A landmark review describing the origin of BPC-157, its remarkable stability and the broad range of gastrointestinal and regenerative research conducted on the peptide.

• Chang CH, Tsai WC, Hsu YM, et al. Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts. Molecular Medicine Reports, 2014.

A key mechanistic study demonstrating enhanced growth hormone receptor expression and fibroblast activity, helping explain BPC-157’s importance in tendon biology.

• Cerovecki T, Bojanic I, Brcic L, et al. Pentadecapeptide BPC 157 Improves Ligament Healing in an Experimental Model. Journal of Orthopaedic Research, 2010.

One of the landmark musculoskeletal studies investigating ligament healing, biomechanical recovery and connective tissue regeneration.

• Sikiric P, Seiwerth S, Grabarevic Z, et al. The Stable Gastric Pentadecapeptide BPC 157 and the Brain–Gut Axis. Current Neuropharmacology, 2016.

A comprehensive review exploring BPC-157 across gastrointestinal, neurological, vascular and regenerative research.

Σχετικό ερευνητικό πλαίσιο

BPC-157 is part of the peptide-based healing and tissue repair research class, commonly studied in models involving angiogenesis, extracellular matrix remodeling, and soft-tissue recovery. For broader context on regenerative pathways and compound interactions, see our Healing & recovery research guide.

Περιηγηθείτε σε όλες τις ενώσεις στο Healing & recovery research category.
Researchers investigating multi-pathway tissue repair and regenerative signaling may also examine:
Thymosing b4 (TB-500) (full sequence) – actin regulation and cellular migration
GHK-Cu (copper peptide complex) – tissue remodeling and collagen-related pathways
KPV (α-MSH fragment) – inflammation-modulating peptide fragment
ARA-290 — erythropoietin-derived tissue protection research
ΣΣ-31 – διερευνήθηκε για τη μιτοχονδριακή λειτουργία και την κυτταρική παραγωγή ενέργειας.

NOTE: This is for educational reference only and does not constitute medical advice.

Disclaimer:
Αυτό το προϊόν πωλείται αποκλειστικά για ερευνητικούς σκοπούς. Δεν προορίζεται για τη διάγνωση, θεραπεία, ίαση ή πρόληψη οποιασδήποτε ασθένειας. Ο αγοραστής αναλαμβάνει πλήρως την ευθύνη για τον σωστό χειρισμό και τη χρήση.