Ipamorelin 5 mg

Description

Selective GH signaling research peptide

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue investigated for its interaction with ghrelin receptor–mediated signaling pathways and endogenous growth hormone release mechanisms. It belongs to the GHRP (growth hormone–releasing peptide) class and is commonly studied in laboratory models examining pulsatile GH secretion, IGF-1 pathway modulation, and hypothalamic–pituitary endocrine regulation.

Researchers are particularly interested in Ipamorelin because of its relatively selective receptor activity compared to earlier growth hormone secretagogues. Experimental models have explored its interaction with growth hormone signaling pathways while evaluating comparatively reduced activity on prolactin, cortisol, and related endocrine pathways.

Ipamorelin is frequently investigated alongside compounds such as CJC-1295 in research models studying synergistic GH-axis modulation and pulsatile endocrine signaling. Compared to broader GHRP compounds such as GHRP-2 and GHRP-6, Ipamorelin is often positioned as a more selective GH secretagogue research model.

For additional information on GH signaling pathways and peptide research compounds, see our growth hormone secretagogues category and peptide reconstitution guide.

Research applications (investigational)

Ipamorelin has been investigated in preclinical and experimental settings for its involvement in:

• Ghrelin receptor (GHSR-1a) signaling pathways
• Pulsatile growth hormone release mechanisms
• GH/IGF-1 axis modulation research
• Hypothalamic–pituitary endocrine signaling models
• Comparative analysis of GHRP-class compounds
• Growth hormone secretagogue pathway interaction
• Endocrine adaptation and recovery-related signaling research

These areas reflect ongoing scientific investigation into endocrine and peptide signaling pathways rather than established applications.

Product characteristics

Purity: ≥ 98% (HPLC)
Appearance: white lyophilized powder
Molecular formula: C₄₀H₅₂N₁₀O₆
Molecular weight: 768.93
Peptide backbone formula shown. Counterion (acetate/TFA) content quantified in batch-specific COA.
Sequence: Gly-Aib-His-D-2-Nal-D-Phe-Lys-NH2
Storage: store lyophilized powder at -20°C, protect from light and moisture. Reconstituted solution should be kept at 2–8°C and used within a short period.

Why choose our Ipamorelin?

≥ 98% purity verified by HPLC.
Produced in GMP-compliant facilities under strict QC protocols.
Each batch carefully lab tested after production (Certificate of Analysis available under product images).
Freeze-dried (lyophilized) for maximum stability and extended shelf life.
Sealed in sterile vials, ready for reconstitution.
Compatible with standard peptide reconstitution protocols using bacteriostatic water

Selected research references

• Raun K et al. “Ipamorelin, the first selective growth hormone secretagogue.” European Journal of Endocrinology, 1998.
• Smith RG et al. “Growth hormone secretagogues: physiology and clinical relevance.” Trends in Endocrinology & Metabolism, 2005.
• Bowers CY. “GH releasing peptides — structure and kinetics.” Journal of Pediatric Endocrinology and Metabolism, 1993.
• Hansen BS et al. “Ipamorelin, a new potent growth hormone-releasing peptide.” American Journal of Physiology, 1999.

Related research context

Ipamorelin belongs to the growth hormone secretagogue research class, which includes compounds investigated for endocrine signaling and GH-axis modulation.

For a broader overview of GH signaling pathways and comparative peptide mechanisms, see our Growth hormone peptides research guide.

Researchers studying GH pathway interaction may also examine:

CJC-1295 (GHRH analogue research peptide)
GHRP-2
GHRP-6

Browse all compounds in the Growth hormone secretagogues category.

Researchers investigating endocrine regulation may also explore compounds in the Metabolic research category, including GLP-1 and multi-pathway incretin agonists.

NOTE: This is for educational reference only and does not constitute medical advice.

Disclaimer
This product is sold for research purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. Buyer assumes full responsibility for proper handling and use.