PT-141 / 10 mg

Beschreibung

Melanocortin peptide for arousal pathway research

PT-141, also known as Bremelanotide, is a synthetic melanocortin receptor agonist investigated for its interaction with central nervous system signaling pathways involved in arousal, motivation, and neuroendocrine response mechanisms. Derived from the melanotan peptide family, PT-141 is primarily studied for its activity at melanocortin receptors MC3R and MC4R within the hypothalamic signaling network.
Unlike PDE5-pathway compounds that act primarily through peripheral vascular mechanisms, PT-141 is researched for centrally mediated signaling effects involving melanocortin pathways associated with desire and arousal-related neurocircuitry. Researchers commonly investigate PT-141 in experimental models involving neuropeptide signaling, dopaminergic pathway interaction, and melanocortin-mediated behavioral response systems.
Due to its mechanism and receptor profile, PT-141 occupies a distinct position within neuroendocrine and melanocortin-related peptide research, often explored alongside compounds derived from α-MSH signaling frameworks.

Research applications (investigational)

PT-141 has been investigated in preclinical and experimental settings for its involvement in:

• Melanocortin receptor signaling (MC3R/MC4R)
• Neuroendocrine arousal pathway research
• Dopaminergic and hypothalamic signaling interaction
• Behavioral and motivational response models
• Central nervous system peptide signaling dynamics
• α-MSH analogue pathway investigation
• Comparative melanocortin pathway analysis

These areas reflect ongoing scientific investigation into neuropeptide-mediated signaling mechanisms rather than established applications.

Product characteristics

Purity: ≥99% (HPLC-tested)
Appearance: Lyophilized white/off-white powder
Molecular formula: C₅₀H₆₈N₁₄O₁₀
Molecular weight: 1025.2
Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH ChemicalBridge Asp2-Lys7
Storage: store lyophilized powder at -20°C, protect from light and moisture. Reconstituted solution should be kept at 2–8°C and used within a short period.

Why choose our PT-141?

High purity verified by HPLC.
Produced in GMP-compliant facilities under strict QC protocols.
Each batch carefully lab tested after production (you can find Certificate of Analysis under product pictures).
Freeze-dried (lyophilized) for maximum stability and extended shelf life.
Sealed in sterile vials, ready for reconstitution.
Wiederherstellung: Typically reconstituted with bacteriostatic water using gentle swirling to maintain peptide stability.

Selected research references

• Molinoff PB et al. PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Annals of the New York Academy of Sciences, 2003.
• King SH et al. Melanocortin receptors, melanotropic peptides and penile erection. Current Topics in Medicinal Chemistry, 2007.
• Edinoff AN et al. Bremelanotide for treatment of female hypoactive sexual desire disorder. Cureus, 2022.
• Clayton AH et al. Phase I randomized placebo-controlled study of bremelanotide. Regulatory Toxicology and Pharmacology, 2017.

Related research context

PT-141 belongs to the broader melanocortin and neuroendocrine peptide research category, focusing on central nervous system signaling and receptor-mediated behavioral pathways.
Researchers exploring related melanocortin pathway models may also examine:
Melanotan II — melanocortin receptor agonist research
Cognitive & neuroresearch peptides — CNS peptide signaling models
Growth hormone secretagogues — neuroendocrine pathway interaction research

NOTE: This is for educational reference only and does not constitute medical advice.

Disclaimer:
This product is sold for research purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. Buyer assumes full responsibility for proper handling and use.