Kisspeptin-10 / 5 mg

Beschreibung

Neuropeptide for reproductive and neuroendocrine signaling research

Kisspeptin-10 is a synthetic peptide fragment derived from the endogenous kisspeptin signaling family, investigated for its interaction with hypothalamic–pituitary–gonadal (HPG) axis regulation and neuroendocrine signaling pathways. Researchers commonly study Kisspeptin-10 for its role in GnRH-mediated hormonal communication and reproductive signaling dynamics.
Unlike direct hormone analogues, Kisspeptin-10 is primarily researched as an upstream regulatory signaling peptide influencing gonadotropin-releasing hormone (GnRH) activity and downstream endocrine pathway interaction. Its signaling profile has made it a widely investigated compound in experimental models involving reproductive endocrinology, neuropeptide communication, and hypothalamic regulation mechanisms.
Researchers are particularly interested in Kisspeptin-10 for studies involving pulsatile hormonal signaling, fertility-related pathway investigation, and central neuroendocrine response systems. Due to its upstream regulatory role, Kisspeptin-10 occupies a distinct position within neuroendocrine and peptide-signaling research.

Research applications (investigational)

Kisspeptin-10 has been investigated in preclinical and experimental settings for its involvement in:

• Hypothalamic–pituitary–gonadal (HPG) axis signaling
• GnRH-mediated neuroendocrine pathway interaction
• Reproductive hormone signaling research
• Pulsatile endocrine communication models
• Fertility-related signaling pathway investigation
• Hypothalamic peptide signaling dynamics
• Comparative neuroendocrine pathway analysis

These areas reflect ongoing scientific investigation into peptide-mediated endocrine signaling mechanisms rather than established applications.

Product characteristics

Purity: ≥99% (HPLC-tested)
Appearance: Lyophilized white/off-white powder
Molecular formula: C₆₃H₈₃N₁₇O₁₄
Molecular weight: 1302.44
Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Storage: store lyophilized powder at -20°C, protect from light and moisture. Reconstituted solution should be kept at 2–8°C and used within a short period.

Why choose our Kisspeptin-10?

High purity verified by HPLC.
Produced in GMP-compliant facilities under strict QC protocols.
Each batch carefully lab tested after production (Certificate of Analysis available under product pictures).
Freeze-dried (lyophilized) for maximum stability and extended shelf life.
Sealed in sterile vials, ready for reconstitution.
Wiederherstellung: Must be reconstituted using appropriate laboratory technique. Due to its physicochemical properties, Kisspeptin may require initial pre-solubilization with dilute acetic acid to achieve full dissolution before dilution with bacteriostatic water or buffered solutions. Inadequate pH conditions or improper handling may result in incomplete dissolution or a whitish/opalescent appearance.

Selected research references

• Seminara SB et al. The GPR54 gene as a regulator of puberty and reproductive signaling. New England Journal of Medicine, 2003.
• Dhillo WS et al. Kisspeptin-54 stimulates gonadotropin release in human males. Journal of Clinical Endocrinology & Metabolism, 2005.
• Oakley AE et al. Kisspeptin signaling in the neuroendocrine regulation of reproduction. Endocrine Reviews, 2009.
• Pinilla L et al. Kisspeptins and reproductive hormone signaling pathways. Physiological Reviews, 2012.

Related research context

Kisspeptin-10 belongs to the broader neuroendocrine and peptide signaling research category, focusing on hypothalamic regulation and reproductive endocrine communication pathways.
Researchers exploring related neuroendocrine signaling models may also examine:

• PT-141 — melanocortin-mediated neuroendocrine signaling research
• Growth hormone secretagogues — hypothalamic and pituitary pathway interaction
• Cognitive & neuroresearch peptides — CNS peptide signaling models

NOTE: This is for educational reference only and does not constitute medical advice.

Disclaimer:
This product is sold for research purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. Buyer assumes full responsibility for proper handling and use.