ARA-290 / 16 mg

Description

Peptide for tissue-protection and inflammatory pathway research

ARA-290 is a synthetic peptide derived from the helix B region of erythropoietin (EPO), investigated for its interaction with tissue-protection signaling pathways without the erythropoietic activity associated with full-length EPO. Researchers commonly study ARA-290 in experimental models involving inflammatory signaling, cellular stress response, and tissue-recovery mechanisms.
Unlike broader regenerative peptides focused primarily on structural tissue remodeling, ARA-290 is primarily researched for receptor-mediated protective signaling and inflammatory pathway modulation. Particular interest exists around its interaction with innate repair mechanisms, microvascular dynamics, and neuroinflammatory research environments.
Due to its selective signaling profile, ARA-290 occupies a distinct position within the healing & recovery research category, often explored in models involving nerve-related tissue response, epithelial stress signaling, and peptide-mediated cellular protection pathways.

Research applications (investigational)

ARA-290 has been investigated in preclinical and experimental settings for its involvement in:
• Tissue-protection signaling pathways
• Inflammatory pathway modulation
• Neuroinflammatory and nerve-response research
• Cellular stress-response mechanisms
• Microvascular and endothelial signaling models
• Peptide-mediated recovery pathway investigation
• Innate repair and protective signaling dynamics
These areas reflect ongoing scientific investigation into peptide-mediated protective mechanisms rather than established applications.

Product characteristics

Purity: ≥99% (HPLC-tested)
Appearance: Lyophilized white/off-white powder
Molecular formula: C₅₁H₈₄N₁₆O₂₁
Molecular weight: 1257.31
Sequence: Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser
Storage: store lyophilized powder at -20°C, protect from light and moisture. Reconstituted solution should be kept at 2–8°C and used within a short period.

Why choose our ARA-290?

• High purity verified by HPLC.
• Produced in GMP-compliant facilities under strict QC protocols.
• Each batch carefully lab tested after production (Certificate of Analysis available under product pictures).
• Freeze-dried (lyophilized) for maximum stability and extended shelf life.
• Sealed in sterile vials, ready for reconstitution.
  Reconstitution: Must be reconstituted using appropriate laboratory technique. Due to its physicochemical properties, ARA-290 requires reconstitution with buffered saline. Inadequate pH conditions or improper handling may result in incomplete dissolution or a whitish/opalescent appearance.

Selected research references

• Brines M et al. ARA 290, a nonerythropoietic peptide engineered from erythropoietin, improves tissue-protective signaling. Proceedings of the National Academy of Sciences, 2008.
• Brines M et al. Erythropoietin-derived peptide protection without hematopoietic activity. Molecular Medicine, 2004.
• Dahan A et al. ARA-290 and inflammatory pathway research in neuropathic models. Molecular Pain, 2013.
• Heij L et al. ARA-290 in small fiber neuropathy research models. Journal of Translational Medicine, 2012.

Related research context

ARA-290 belongs to the Healing & recovery peptide research category, with stronger emphasis on tissue-protection and inflammatory signaling pathways.
Researchers investigating complementary recovery and cellular-response models may also examine:
• KPV — inflammatory signaling and epithelial pathway research
• BPC-157 — tissue signaling and angiogenesis research
• TB-500 (Thymosin β4) — migration and cytoskeletal pathway investigation
• GHK-Cu — extracellular remodeling and skin-related peptide signaling
For broader context, see the Healing & recovery research guide.

NOTE: This is for educational reference only and does not constitute medical advice.

Disclaimer:
This product is sold for research purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. Buyer assumes full responsibility for proper handling and use.