Epitalon 10 mg

Beschreibung

Epitalon (also known as Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly; AEDG) derived from Epithalamin, a peptide complex originally isolated from the pineal gland.

It has become one of the most recognised research peptides in longevity science because published studies have investigated its relationship with telomerase activation, telomere maintenance, circadian rhythm and healthy aging. Although the peptide is frequently discussed in longevity research, much of the evidence comes from laboratory and preclinical studies, with relatively limited independent human research.

Why Epitalon is widely investigated

Published research has investigated Epitalon in relation to:

• gesundes Altern
• telomerase activation
• telomere biology
• cellular senescence
• circadian rhythm
• melatonin regulation
• pineal gland function
• oxidative stress
• longevity research

Epitalon remains one of the few research peptides specifically developed to investigate biological aging rather than metabolism, growth hormone or tissue repair.

How Epitalon works

Current research has explored several potential mechanisms.

Telomerase activity

The best-known studies investigated whether Epitalon can increase expression of telomerase (hTERT) and influence telomere maintenance in cultured human cells. Independent laboratory work published in 2025 provided additional support for these observations, although clinical significance remains uncertain.

Pineal gland research

Epitalon has also been investigated for its relationship with pineal gland biology and melatonin synthesis, making it relevant to research on circadian rhythm and age-related changes in endocrine function.

Gesund altern

Animal studies have explored the relationship between Epitalon, cellular aging and lifespan, while human research has remained comparatively limited. Current evidence supports continued investigation but does not establish clinical longevity effects.

Oxidative stress

Researchers have also investigated Epitalon’s interaction with oxidative stress and age-related cellular regulation as part of broader longevity research.

Why Epitalon became one of the best-known longevity peptides

Few research peptides have generated as much discussion in longevity science as Epitalon.

Interest largely stems from early publications reporting telomerase activation and possible effects on cellular aging. However, one important limitation should be recognised: most of the published longevity literature originates from a single research group, and independent confirmation has only recently begun to emerge at the cellular level. Large placebo-controlled human trials remain unavailable.

For this reason, Epitalon is best viewed as one of the most promising investigational longevity peptides rather than an established anti-aging intervention.

Menschliche und präklinische Forschung

Veröffentlichte Forschung umfasst:

• telomerase biology
• telomere maintenance
• pineal gland physiology
• melatonin regulation
• circadian rhythm
• gesundes Altern
• lifespan research
• oxidative stress

Laboratory findings are encouraging, but clinical evidence remains limited compared with more established research peptides.

Veröffentlichte Sicherheitsbeobachtungen

Most published human data involve relatively small studies. Early investigations generally reported good tolerability, but comprehensive long-term safety data are lacking. Researchers also note that because Epitalon has been investigated for telomerase activation, additional research is needed to better understand its long-term biological effects before firm conclusions can be drawn.

Produkteigenschaften

Anwendung: Labor- und analytische Forschung
Verwendungseinschränkung: Nicht zum menschlichen Verzehr bestimmt; nicht für medizinische, veterinärmedizinische oder kosmetische Zwecke
Hergestellt in GMP-konformen Anlagen unter strengen Qualitätskontrollprotokollen.
Jede Charge wird nach der Produktion sorgfältig im Labor getestet (das Analysezertifikat finden Sie unter den Produktbildern).
Gefriergetrocknet (lyophilisiert) für maximale Stabilität und längere Haltbarkeit.
Steril in Fläschchen abgefüllt, bereit zur Rekonstitution.
Reinheit: ≥98,1 % (HPLC-geprüft)
Aussehen: Lyophilisiertes weißes/weißliches Pulver
Summenformel: C₁₄H₂₂N₄O₉
Molekulargewicht: 390,34
Ala-Glu-Asp-Gly
Lagerung: Ungeöffnete lyophilysierte Fläschchen werden am besten gekühlt bei 2–8 °C gelagert, was die von unserem Produktionspartner bestätigte Lagerungsmethode ist und für bis zu 24 Monate geeignet ist. Kühlung wird bevorzugt, da sie unnötige Gefrier-Tau-Zyklen bei der routinemäßigen Handhabung minimiert. Wenn eine wesentlich längerfristige Lagerung erforderlich ist, können ungeöffnete lyophilysierte Fläschchen auch gefroren aufbewahrt werden. Nach der Rekonstitution immer bei 2–8 °C lagern und nicht einfrieren.

Rekonstitution und Handhabung

Epitalon is supplied as a lyophilised vial and should be handled using standard peptide reconstitution procedures appropriate to the research setting. Must be reconstituted with Bakteriostatisches Wasser Vor Gebrauch. Um die strukturelle Integrität zu erhalten, geben Sie das gewählte Lösungsmittel langsam an der Innenwand des Fläschchens hinzu und nicht direkt auf den Peptidkuchen, und vermeiden Sie kräftiges Schütteln. Sanftes Schwenken ist im Allgemeinen ausreichend, sobald sich das Peptid vollständig gelöst hat. Standardmäßige Laborpraxis beinhaltet auch, gekühlte Fläschchen Raumtemperatur erreichen zu lassen, bevor sie rekonstituiert werden, um die Kondensation im Fläschchen zu minimieren.

Für weitere Informationen zur Lösungsmittelauswahl, zur Konzentrationsplanung und zur Lagerung siehe das vollständige Leitfaden zur Peptidrekonstitution und Rekonstitutionsrechner.

Ausgewählte Referenzen

• Khavinson V, Bondarev I, Butyugov A. Epitalon Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells, Bulletin of Experimental Biology and Medicine, 2003

The landmark publication reporting telomerase activation and telomere extension in cultured human cells.

• Al-Dulaimi A, Thomas R, Matta C, Roberts T. Independent Investigation of Epitalon-Induced Telomere Extension in Human Cell Lines, 2025

One of the first independent studies outside the original Russian research programme confirming telomere extension in human cell models and exploring underlying mechanisms.

• Khavinson V, Anisimov V. Pineal Peptides and Aging

A series of publications investigating Epitalon’s relationship with pineal function, melatonin regulation and healthy aging.

• Zhou et al. Recent Perspectives on Epitalon and Healthy Aging, 2025–2026 reviews

Modern reviews discussing current evidence, limitations and future directions for Epitalon research.

Häufig gestellte Fragen

What is Epitalon?

Epitalon is a synthetic tetrapeptide derived from Epithalamin. It is widely investigated for healthy aging, telomerase activity, telomere biology and pineal gland research.

Why is Epitalon associated with longevity research?

Early laboratory studies suggested that Epitalon may influence telomerase activity and telomere maintenance. These findings made it one of the best-known peptides in longevity research, although large independent human trials remain unavailable.

Does Epitalon lengthen telomeres?

Cell culture studies have reported telomerase activation and telomere extension, and recent independent laboratory work has supported these observations. However, whether these findings translate into meaningful clinical outcomes in humans has not yet been established.

Why is Epitalon linked to melatonin?

Research has investigated Epitalon’s effects on the pineal gland and melatonin synthesis, making it relevant to studies of circadian rhythm and age-related endocrine changes.

What research areas commonly investigate Epitalon?

Published research includes healthy aging, telomerase biology, telomere maintenance, pineal gland physiology, melatonin regulation, circadian rhythm and oxidative stress.

Why is Epitalon considered controversial?

The peptide has promising mechanistic and preclinical data, but much of the supporting literature originates from a single research programme. Independent replication has begun to emerge in laboratory models, yet robust randomized human trials remain lacking.

Ist dieses Produkt für den menschlichen Gebrauch bestimmt?

No. Epitalon supplied by LIFE Peptide is provided strictly for laboratory and analytical research. It is not intended for human consumption, diagnosis, treatment or prevention of disease. Any discussion of published studies summarises the scientific literature relating to the Epitalon molecule rather than the intended use of this product.

Verwandter Forschungskontext

Epitalon is frequently discussed alongside other research peptides investigating healthy aging, mitochondrial biology and cellular resilience.

MOTS-c – investigated for mitochondrial metabolism, exercise adaptation and healthy aging.
GHK-Cu – studied in relation to tissue repair, extracellular matrix remodelling and age-related skin biology.
DSIP – investigated for sleep physiology, circadian biology and neuroendocrine regulation.
Semax – researched for neuroprotection and cognitive function.
Selank – investigated in stress adaptation and neuroendocrine regulation.
SS-31 – investigated for mitochondrial function and cellular energy production.

Although these peptides are often grouped within longevity research, each investigates different biological pathways and should not be considered interchangeable.

HINWEIS: Dies dient nur zu Bildungszwecken und stellt keine medizinische Beratung dar.

Haftungsausschluss
Dieses Produkt wird ausschließlich zu Forschungszwecken verkauft. Es ist nicht dazu bestimmt, Krankheiten zu diagnostizieren, zu behandeln, zu heilen oder zu verhindern. Der Käufer übernimmt die volle Verantwortung für die ordnungsgemäße Handhabung und Verwendung.