GHRP-2 / 5 mg

Description

Ghrelin receptor–mediated GH signaling peptide

GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide growth hormone secretagogue investigated for its interaction with ghrelin receptor (GHSR-1a)–mediated signaling pathways and endogenous growth hormone release mechanisms. It belongs to the GHRP class and is commonly studied in laboratory models examining pulsatile GH secretion, IGF-1 pathway modulation, and hypothalamic–pituitary endocrine regulation.

Researchers are particularly interested in GHRP-2 because of its potent interaction with growth hormone signaling pathways and its broader endocrine activity profile compared to more selective secretagogues. Experimental models have explored its effects on GH release dynamics alongside its interaction with additional hormonal pathways, including cortisol and prolactin signaling.

GHRP-2 is frequently investigated alongside GHRH analogues such as CJC-1295 and Tesamorelin in research models studying synergistic GH-axis modulation and coordinated endocrine signaling. Compared to more selective compounds such as Ipamorelin, GHRP-2 is often used as a broader GH secretagogue model in comparative endocrine research.

For a broader overview of growth hormone secretagogues, pulsatile GH signaling, and GHRP-class compounds, see our Growth hormone peptides research guide.

Research applications (investigational)

GHRP-2 has been investigated in preclinical and experimental settings for its involvement in:

• Ghrelin receptor (GHSR-1a) signaling pathways
• Pulsatile growth hormone release mechanisms
• GH/IGF-1 axis modulation research
• Hypothalamic–pituitary endocrine pathway models
• Comparative analysis of GHRP-class compounds
• Multi-pathway endocrine signaling interaction studies
• Hormonal response modeling involving GH, cortisol, and prolactin pathways

These areas reflect ongoing scientific investigation into endocrine and peptide signaling pathways rather than established applications.

Product characteristics

Purity: ≥98% (HPLC-tested)
Appearance: Lyophilized white/off-white powder
Molecular formula: C₄₇H₅₈N₁₀O₇
Molecular weight: 818.0 g/mol
Sequence: Gly-D-Ala-D-βNal-Ala-Trp-D-Phe-Lys-NH2
Storage: store lyophilized powder at -20°C, protect from light and moisture. Reconstituted solution should be kept at 2–8°C and used within a short period.

Why choose our GHRP-2?

≥ 98% purity verified by HPLC.
Produced in GMP-compliant facilities under strict QC protocols.
Each batch carefully lab tested after production (you can find Certificate of Analysis under product pictures).
Freeze-dried (lyophilized) for maximum stability and extended shelf life.
Sealed in sterile vials, ready for reconstitution.
Compatible with standard peptide reconstitution protocols using bacteriostatic water

Selected research references

• Bowers CY et al. “Structure-activity relationships of growth hormone–releasing peptides.” Endocrinology, 1990.
• Smith RG et al. “Growth hormone secretagogues: physiology and clinical relevance.” Trends in Endocrinology & Metabolism, 2005.
• Kojima M et al. “Ghrelin is a growth-hormone-releasing acylated peptide.” Nature, 1999.
• Arvat E et al. “GHRP-2 and endocrine responses in humans.” Journal of Endocrinological Investigation, 1997.

Related research context

GHRP-2 belongs to the growth hormone secretagogue research class, which includes peptides investigated for endocrine signaling, GH-axis modulation, and pulsatile hormone release mechanisms.
For a broader overview of GH signaling pathways and comparative peptide mechanisms, see our Growth hormone peptides research guide.
Researchers studying GH-axis interaction may also examine:

Ipamorelin
CJC-1295 (no DAC)
Tesamorelin
GHRP-6

Browse all compounds in the Growth hormone secretagogues category.

Researchers investigating endocrine regulation may also explore compounds in the Metabolic research category, including GLP-1 and multi-pathway incretin agonists.

NOTE: This is for educational reference only and does not constitute medical advice.

Disclaimer:
This product is sold for research purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. Buyer assumes full responsibility for proper handling and use.